Biobased Antimicrobial Coatings: Layer-by-Layer Assemblies Based on Natural Polyphenols

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F26%3A0197376" target="_blank" >RIV/00216305:26310/26:0197376 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acsapm.4c03681" target="_blank" >https://pubs.acs.org/doi/10.1021/acsapm.4c03681</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acsapm.4c03681" target="_blank" >10.1021/acsapm.4c03681</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biobased Antimicrobial Coatings: Layer-by-Layer Assemblies Based on Natural Polyphenols

Popis výsledku v původním jazyce

Natural polyphenols possess inherent defensive properties against pathogens. This study investigated the radical scavenging and antimicrobial activity of biobased polyphenol nanoparticles (PNPs) derived from grape seeds. Scanning electron micrographs and dynamic light scattering confirmed the synthesized nanoparticles’ spherical shape, showing an average hydrodynamic radius of 93.9 ± 4.0 nm. The PNPs exhibited radical scavenging activity at about 433 mg Trolox per gram and a microbial inhibitory effect against Micrococcus luteus and Escherichia coli. The negatively charged PNPs were used to prepare thin multilayer films combined with positively charged polyelectrolytes such as poly(allylamine hydrochloride), poly-l-lysine, poly(diallyldimethylammonium chloride), or polyethylenimine. The viscoelastic properties of polyelectrolyte/PNP films were monitored using a quartz crystal microbalance with dissipation. The PNPs showed the best interface compatibility with poly-l-lysine (PLL), enabling the preparation of mechanically stable thin multilayer films. The antioxidant activity of PLL/PNP films was 72 ± 6 μg Trolox per cm2 at pH 10. The PLL/PNP films displayed antimicrobial activity against M. luteus and E. coli, with growth inhibition of 50.7 ± 0.6% and 12.1 ± 0.6%, respectively. The prepared biobased PLL/PNP Layer-by-Layer assemblies can potentially prevent biofilm formation on a large spectrum of materials.

Název v anglickém jazyce

Biobased Antimicrobial Coatings: Layer-by-Layer Assemblies Based on Natural Polyphenols

Popis výsledku anglicky

Natural polyphenols possess inherent defensive properties against pathogens. This study investigated the radical scavenging and antimicrobial activity of biobased polyphenol nanoparticles (PNPs) derived from grape seeds. Scanning electron micrographs and dynamic light scattering confirmed the synthesized nanoparticles’ spherical shape, showing an average hydrodynamic radius of 93.9 ± 4.0 nm. The PNPs exhibited radical scavenging activity at about 433 mg Trolox per gram and a microbial inhibitory effect against Micrococcus luteus and Escherichia coli. The negatively charged PNPs were used to prepare thin multilayer films combined with positively charged polyelectrolytes such as poly(allylamine hydrochloride), poly-l-lysine, poly(diallyldimethylammonium chloride), or polyethylenimine. The viscoelastic properties of polyelectrolyte/PNP films were monitored using a quartz crystal microbalance with dissipation. The PNPs showed the best interface compatibility with poly-l-lysine (PLL), enabling the preparation of mechanically stable thin multilayer films. The antioxidant activity of PLL/PNP films was 72 ± 6 μg Trolox per cm2 at pH 10. The PLL/PNP films displayed antimicrobial activity against M. luteus and E. coli, with growth inhibition of 50.7 ± 0.6% and 12.1 ± 0.6%, respectively. The prepared biobased PLL/PNP Layer-by-Layer assemblies can potentially prevent biofilm formation on a large spectrum of materials.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACS Applied Polymer Materials

ISSN

—

e-ISSN

2637-6105

Svazek periodika

7

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

3601-3610

Kód UT WoS článku

001445707500001

EID výsledku v databázi Scopus

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