Revisiting lab-on-a-chip technology for drug discovery

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F12%3APU103020" target="_blank" >RIV/00216305:26620/12:PU103020 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1038/nrd3799" target="_blank" >http://dx.doi.org/10.1038/nrd3799</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/nrd3799" target="_blank" >10.1038/nrd3799</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Revisiting lab-on-a-chip technology for drug discovery

Popis výsledku v původním jazyce

The field of microfluidics or lab-on-a-chip technology aims to improve and extend the possibilities of bioassays, cell biology and biomedical research based on the idea of miniaturization. Microfluidic systems allow more accurate modelling of physiological situations for both fundamental research and drug development, and enable systematic high-volume testing for various aspects of drug discovery. Microfluidic systems are in development that not only model biological environments but also physically mimic biological tissues and organs; such 'organs on a chip' could have an important role in expediting early stages of drug discovery and help reduce reliance on animal testing. This Review highlights the latest lab-on-a-chip technologies for drug discovery and discusses the potential for future developments in this field.

Název v anglickém jazyce

Revisiting lab-on-a-chip technology for drug discovery

Popis výsledku anglicky

The field of microfluidics or lab-on-a-chip technology aims to improve and extend the possibilities of bioassays, cell biology and biomedical research based on the idea of miniaturization. Microfluidic systems allow more accurate modelling of physiological situations for both fundamental research and drug development, and enable systematic high-volume testing for various aspects of drug discovery. Microfluidic systems are in development that not only model biological environments but also physically mimic biological tissues and organs; such 'organs on a chip' could have an important role in expediting early stages of drug discovery and help reduce reliance on animal testing. This Review highlights the latest lab-on-a-chip technologies for drug discovery and discusses the potential for future developments in this field.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

NATURE REVIEWS DRUG DISCOVERY

ISSN

1474-1776

e-ISSN

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Svazek periodika

2012 (11)

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

620-632

Kód UT WoS článku

000307101100020

EID výsledku v databázi Scopus

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