Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications

Popis výsledku v původním jazyce

Alumina toughened zirconia (ATZ) / calcium phosphate (Ca-P) composite scaffolds were fabricated via polymer replica technique, the technique that best mimics the macrostructure of trabecular bone. Strong inert core based on ATZ was composed of microsizedzirconia powder bonded by colloidal solution of boehmite. Sintered scaffolds were coated by suspension composed of hydroxyapatite / tricalcium phosphate powders and PVB binder. Scaffolds exhibited well-interconnected structure with pore sizes ranging from 300 to 1200 ?m. Different porosity (50-98%) was achieved by repeating the replication process 1-6 times. The Ca-P coating with a thickness of about 50 ?m was firmly adhered to the ATZ core. Neither of tested materials was cytotoxic. The apatite formation, appeared on the surface of coated scaffolds after immersion in simulated body fluid (SBF) indicated a good bioactivity of the ATZ/Ca-P composite.

Název v anglickém jazyce

Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications

Popis výsledku anglicky

Alumina toughened zirconia (ATZ) / calcium phosphate (Ca-P) composite scaffolds were fabricated via polymer replica technique, the technique that best mimics the macrostructure of trabecular bone. Strong inert core based on ATZ was composed of microsizedzirconia powder bonded by colloidal solution of boehmite. Sintered scaffolds were coated by suspension composed of hydroxyapatite / tricalcium phosphate powders and PVB binder. Scaffolds exhibited well-interconnected structure with pore sizes ranging from 300 to 1200 ?m. Different porosity (50-98%) was achieved by repeating the replication process 1-6 times. The Ca-P coating with a thickness of about 50 ?m was firmly adhered to the ATZ core. Neither of tested materials was cytotoxic. The apatite formation, appeared on the surface of coated scaffolds after immersion in simulated body fluid (SBF) indicated a good bioactivity of the ATZ/Ca-P composite.

Druh

D - Stať ve sborníku

CEP obor

JH - Keramika, žáruvzdorné materiály a skla

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Multi-scale Design of Advanced Materials - Conference Proceedings

ISBN

978-80-214-5146-9

ISSN

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e-ISSN

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Počet stran výsledku

7

Strana od-do

93-99

Název nakladatele

Neuveden

Místo vydání

Neuveden

Místo konání akce

Velké Bílovice

Datum konání akce

28. 5. 2015

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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