Double resin casting micro computed tomography (DUCT) of biliary and vascular system

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F18%3APU140018" target="_blank" >RIV/00216305:26620/18:PU140018 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/18:PU128018

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Double resin casting micro computed tomography (DUCT) of biliary and vascular system

Popis výsledku v původním jazyce

Malformation of lumenized structures, such as the intrahepatic circulatory or biliary systems, is a hallmark of several liver disorders, from vascular hepatic disease to Alagille syndrome. Liver architecture in mice has typically been studied using 2D sections and, more recently, with thicker tissue sections and whole mount immunofluorescence, neither of which resolves 3D architecture adequately. Importantly, the vascular and biliary systems are inter-dependent, and we therefore aimed to develop a robust method to image, digitalize and quantify 3D architecture of the biliary and vascular systems in tandem.

Název v anglickém jazyce

Double resin casting micro computed tomography (DUCT) of biliary and vascular system

Popis výsledku anglicky

Malformation of lumenized structures, such as the intrahepatic circulatory or biliary systems, is a hallmark of several liver disorders, from vascular hepatic disease to Alagille syndrome. Liver architecture in mice has typically been studied using 2D sections and, more recently, with thicker tissue sections and whole mount immunofluorescence, neither of which resolves 3D architecture adequately. Importantly, the vascular and biliary systems are inter-dependent, and we therefore aimed to develop a robust method to image, digitalize and quantify 3D architecture of the biliary and vascular systems in tandem.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10605 - Developmental biology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů