Optimizing the Laser Ablation of Soft Tissues

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU133737" target="_blank" >RIV/00216305:26620/19:PU133737 - isvavai.cz</a>

Výsledek na webu

<a href="http://libs.ceitec.cz/files/281/213.pdf" target="_blank" >http://libs.ceitec.cz/files/281/213.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Optimizing the Laser Ablation of Soft Tissues

Popis výsledku v původním jazyce

The issue of laser-matter interaction is of great importance in the material analysis using laser-ablation-based techniques, such as Laser-Induced Breakdown Spectroscopy (LIBS). The distribution of elements in soft tissues is an important source of information, which can facilitate diagnosing. LIBS is shown to be a viable option for qualitative imaging of specific elements in biological tissue material. The laser ablation is driven namely by the proper selection of laser wavelength and irradiance. Optimal soft tissue measurement parameters were determined by the pulse wavelength optimization process. Tested samples were mouse kidneys fixed in paraffin. Gradually, all possible wavelengths of laser pulse were tested: 1064 nm, 532 nm and 266 nm. The energy within the range from 1 mJ to 25 mJ, setting with a step of 5 mJ, was tested for energy laser pulse. The signal dependence of individual elements was monitored with respect to their concentration. Moreover, the resulting wavelength and laser energy val

Název v anglickém jazyce

Optimizing the Laser Ablation of Soft Tissues

Popis výsledku anglicky

The issue of laser-matter interaction is of great importance in the material analysis using laser-ablation-based techniques, such as Laser-Induced Breakdown Spectroscopy (LIBS). The distribution of elements in soft tissues is an important source of information, which can facilitate diagnosing. LIBS is shown to be a viable option for qualitative imaging of specific elements in biological tissue material. The laser ablation is driven namely by the proper selection of laser wavelength and irradiance. Optimal soft tissue measurement parameters were determined by the pulse wavelength optimization process. Tested samples were mouse kidneys fixed in paraffin. Gradually, all possible wavelengths of laser pulse were tested: 1064 nm, 532 nm and 266 nm. The energy within the range from 1 mJ to 25 mJ, setting with a step of 5 mJ, was tested for energy laser pulse. The signal dependence of individual elements was monitored with respect to their concentration. Moreover, the resulting wavelength and laser energy val

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů