Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU134459" target="_blank" >RIV/00216305:26620/19:PU134459 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081723:_____/20:00532392 RIV/61389013:_____/20:00532392

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0144861719313761" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0144861719313761</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.carbpol.2019.115708" target="_blank" >10.1016/j.carbpol.2019.115708</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Popis výsledku v původním jazyce

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 ± 250 nm) and outer fiber diameter of (2.5 ± 0.5 µm). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.

Název v anglickém jazyce

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Popis výsledku anglicky

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 ± 250 nm) and outer fiber diameter of (2.5 ± 0.5 µm). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Carbohydrate Polymers

ISSN

0144-8617

e-ISSN

1879-1344

Svazek periodika

5

Číslo periodika v rámci svazku

25

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

15

Strana od-do

101-117

Kód UT WoS článku

000504402300017

EID výsledku v databázi Scopus

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