RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F20%3APU141439" target="_blank" >RIV/00216305:26620/20:PU141439 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.insterdisciplinarymeeting.cz/shell/sbornik-2020.pdf" target="_blank" >http://www.insterdisciplinarymeeting.cz/shell/sbornik-2020.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

Popis výsledku v původním jazyce

In this work, hydrophobic and amphiphilic bioresorbable electrospun microfibers were used to reinforce the calcium phosphate bone cement. Addition of these fibers increased mechanical properties in terms of compressive strength. The fiber amount was optimized in terms of final cement injectability. X-ray diffraction analysis proved full transformation of calcium phosphate to calcium defficient hydroxyapatite after fiber addition. Scanning electron microscopy was used to study microstructure and failure modes at crack interfaces. For better resorption rates, microporositi was modulated. Experiments proved utilization of microfibers as bone cement reinforcement and when loaded with bioactive molecules, they can be used in cements as drug delivery systems.

Název v anglickém jazyce

RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

Popis výsledku anglicky

In this work, hydrophobic and amphiphilic bioresorbable electrospun microfibers were used to reinforce the calcium phosphate bone cement. Addition of these fibers increased mechanical properties in terms of compressive strength. The fiber amount was optimized in terms of final cement injectability. X-ray diffraction analysis proved full transformation of calcium phosphate to calcium defficient hydroxyapatite after fiber addition. Scanning electron microscopy was used to study microstructure and failure modes at crack interfaces. For better resorption rates, microporositi was modulated. Experiments proved utilization of microfibers as bone cement reinforcement and when loaded with bioactive molecules, they can be used in cements as drug delivery systems.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů