Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU142528" target="_blank" >RIV/00216305:26620/21:PU142528 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf" target="_blank" >http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing
Popis výsledku v původním jazyce
Wound healing is a process which requires an appropriate approach for effective and accelerated healing. Variety of materials including natural and synthetic polymers are used for the production of films, gels, hydrogels or sponges. Gum Karaya (GK) is a natural polymer, resin able to form a gel with antimicrobial properties supporting the healing process1. Here, GK was modified with synthetic hydrophilic gelling polymers and emollient component to obtain soft, elastic and transparent film via freeze-drying technique. To increase antimicrobial activity an antiseptic agent octenidine dihydrochloride (OCT) was added due to its antimicrobial effect, low absorption to the skin and no systemic toxicity. OCT is widely used antiseptics for topical wounds (acute, chronic) with antimicrobial effect against Gram-positive and Gram-negative bacteria including resistant pathogens.
Název v anglickém jazyce
Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing
Popis výsledku anglicky
Wound healing is a process which requires an appropriate approach for effective and accelerated healing. Variety of materials including natural and synthetic polymers are used for the production of films, gels, hydrogels or sponges. Gum Karaya (GK) is a natural polymer, resin able to form a gel with antimicrobial properties supporting the healing process1. Here, GK was modified with synthetic hydrophilic gelling polymers and emollient component to obtain soft, elastic and transparent film via freeze-drying technique. To increase antimicrobial activity an antiseptic agent octenidine dihydrochloride (OCT) was added due to its antimicrobial effect, low absorption to the skin and no systemic toxicity. OCT is widely used antiseptics for topical wounds (acute, chronic) with antimicrobial effect against Gram-positive and Gram-negative bacteria including resistant pathogens.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
10404 - Polymer science
Návaznosti výsledku
Projekt
<a href="/cs/project/NU20-05-00166" target="_blank" >NU20-05-00166: Nové přístupy k hojení infikovaných ran pomocí hydrogelů z přírodní pryskyřice Gum Karaya modifikovaných inovativními komponenty cílenými na multirezistentní kmeny bakterií</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů