Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU150120" target="_blank" >RIV/00216305:26620/23:PU150120 - isvavai.cz</a>
Výsledek na webu
<a href="https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-981-16-6775-6_9" target="_blank" >10.1007/978-981-16-6775-6_9</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography
Popis výsledku v původním jazyce
Many novel biomaterials are recently investigated for use in spinal fusion surgery, especially in lumbar interbody fusion. The X-ray microCT as a tool is widely used for evaluating how successfully those biomaterials can perform a vertebral fusion. However, the current methodologies of microCT image assessment are based on visual evaluation by the operator. In this paper, we propose a methodology for how such biomaterials can be investigated in pre-clinical studies by investigating fused vertebrae morphology. We utilized microCT scans of pigs’ fused vertebrae to develop a fully automatic approach, which can characterize the morphometry of the bone in the fused region. A surface mesh model was created to extract the newly formed bone tissue between fused vertebrae in the microCT data. Extracted bone tissue was consequently evaluated according to the selected morphometric parameters. Characterization of the newly formed bone properties in the intervertebral area can be utilized to evaluate the osteogenesis function of implants used in lumbar interbody fusion surgery.
Název v anglickém jazyce
Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography
Popis výsledku anglicky
Many novel biomaterials are recently investigated for use in spinal fusion surgery, especially in lumbar interbody fusion. The X-ray microCT as a tool is widely used for evaluating how successfully those biomaterials can perform a vertebral fusion. However, the current methodologies of microCT image assessment are based on visual evaluation by the operator. In this paper, we propose a methodology for how such biomaterials can be investigated in pre-clinical studies by investigating fused vertebrae morphology. We utilized microCT scans of pigs’ fused vertebrae to develop a fully automatic approach, which can characterize the morphometry of the bone in the fused region. A surface mesh model was created to extract the newly formed bone tissue between fused vertebrae in the microCT data. Extracted bone tissue was consequently evaluated according to the selected morphometric parameters. Characterization of the newly formed bone properties in the intervertebral area can be utilized to evaluate the osteogenesis function of implants used in lumbar interbody fusion surgery.
Klasifikace
Druh
D - Stať ve sborníku
CEP obor
—
OECD FORD obor
20601 - Medical engineering
Návaznosti výsledku
Projekt
<a href="/cs/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Kvalitní interní granty VUT</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2023
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název statě ve sborníku
Medical Imaging and Computer-Aided Diagnosis
ISBN
978-981-16-6774-9
ISSN
1876-1100
e-ISSN
—
Počet stran výsledku
10
Strana od-do
101-110
Název nakladatele
Springer Nature Singapore
Místo vydání
Singapore
Místo konání akce
University of Leicester, UK
Datum konání akce
20. 11. 2022
Typ akce podle státní příslušnosti
WRD - Celosvětová akce
Kód UT WoS článku
—