Inactivation of influenza virus as representative of enveloped RNA viruses on photocatalytically active nanoparticle and nanotubular TiO2 surfaces

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F24%3APU151598" target="_blank" >RIV/00216305:26620/24:PU151598 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388963:_____/24:00583888 RIV/00216275:25310/24:39921815 RIV/60461373:22310/24:43928445 RIV/00216208:11310/24:10478714

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0920586124000051?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0920586124000051?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cattod.2024.114511" target="_blank" >10.1016/j.cattod.2024.114511</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Inactivation of influenza virus as representative of enveloped RNA viruses on photocatalytically active nanoparticle and nanotubular TiO2 surfaces

Popis výsledku v původním jazyce

The recent pandemic showed us that there is a strong demand for standardized methods to evaluate the antiviral activity of different materials using enveloped RNA viruses (e.g. SARS-CoV-2, influenza virus). Virucidal activity can be achieved as a result of photoexcitation of a TiO2 photocatalyst under UV illumination. All standardized methods evaluating the virucidal activity of photocatalytic surfaces use bacteriophage Q -beta, a representative of small non -enveloped viruses. This work was thus devoted to the evaluation of the virucidal efficiency of photocatalytically active nanostructured TiO2 surfaces (nanotubular and nanoparticle) to inactivate the influenza virus with particular interest paid to the methodology of virucidal testing and the influence of the surface nanostructure (porosity). Two different TiO2 nanostructures were used in this study, namely nanoparticle and nanotubular structures. A significant decrease in the amount of viral RNA and titre was obtained after rinsing, because the virus was retained on the surface of the nanostructured TiO2 during exposure in the dark. The decrease can be understood as an additional effect of the surface porosity on the TiO2 virucidal activity after UV illumination. However, this fact was taken into account in the calculation of virucidal activity due to UV light. Both nanostructured TiO2 coatings have comparable porosity and thickness, but the photocatalytic activity (to oxidatively degrade aqueous pollutants) is higher for the nanoparticle than for the nanotubular surface. On the other hand, the virucidal activity is much higher for the nanotubular surface. This can be explained by the uniform and open structure of nanotubes resulting in a lower amount of virus being retained on the surface under dark conditions and the high surface area of the nanotubes.

Název v anglickém jazyce

Inactivation of influenza virus as representative of enveloped RNA viruses on photocatalytically active nanoparticle and nanotubular TiO2 surfaces

Popis výsledku anglicky

The recent pandemic showed us that there is a strong demand for standardized methods to evaluate the antiviral activity of different materials using enveloped RNA viruses (e.g. SARS-CoV-2, influenza virus). Virucidal activity can be achieved as a result of photoexcitation of a TiO2 photocatalyst under UV illumination. All standardized methods evaluating the virucidal activity of photocatalytic surfaces use bacteriophage Q -beta, a representative of small non -enveloped viruses. This work was thus devoted to the evaluation of the virucidal efficiency of photocatalytically active nanostructured TiO2 surfaces (nanotubular and nanoparticle) to inactivate the influenza virus with particular interest paid to the methodology of virucidal testing and the influence of the surface nanostructure (porosity). Two different TiO2 nanostructures were used in this study, namely nanoparticle and nanotubular structures. A significant decrease in the amount of viral RNA and titre was obtained after rinsing, because the virus was retained on the surface of the nanostructured TiO2 during exposure in the dark. The decrease can be understood as an additional effect of the surface porosity on the TiO2 virucidal activity after UV illumination. However, this fact was taken into account in the calculation of virucidal activity due to UV light. Both nanostructured TiO2 coatings have comparable porosity and thickness, but the photocatalytic activity (to oxidatively degrade aqueous pollutants) is higher for the nanoparticle than for the nanotubular surface. On the other hand, the virucidal activity is much higher for the nanotubular surface. This can be explained by the uniform and open structure of nanotubes resulting in a lower amount of virus being retained on the surface under dark conditions and the high surface area of the nanotubes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10400 - Chemical sciences

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CATALYSIS TODAY

ISSN

0920-5861

e-ISSN

1873-4308

Svazek periodika

430

Číslo periodika v rámci svazku

114511

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

„“-„“

Kód UT WoS článku

001170622800001

EID výsledku v databázi Scopus

2-s2.0-85185187756