Defining the seriousness of proliferative vitreoretinopathy by aspiration of cytokines from the anterior chamber
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F13%3A10139746" target="_blank" >RIV/00669806:_____/13:10139746 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.2217/bmm.13.65" target="_blank" >http://dx.doi.org/10.2217/bmm.13.65</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2217/bmm.13.65" target="_blank" >10.2217/bmm.13.65</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Defining the seriousness of proliferative vitreoretinopathy by aspiration of cytokines from the anterior chamber
Popis výsledku v původním jazyce
Proliferative vitreoretinopathy is the major cause of retinal detachment surgery failure. Our prospective cohort study of 27 eyes aimed to determine intraocular levels of growth factors and cytokines in patients with retinal detachment with various degrees of severity of proliferative vitreoretinopathy using multiplex xMAP((R)) Technology. Patients & methods: The concentrations of 12 proangiogenic, antiangiogenic, inflammatory and neurotrophic factors were measured from 0.05-ml samples of intraocular fluid using multiplex xMAP Technology. The results were compared with levels of various factors, which were measured in samples from the control group of 31 eyes prior to senile cataract surgery. Results: The concentration of the MCP-1 cytokine was found to be higher in eyes with retinal detachment compared with the control group. The concentration of VEGF was found to be higher in eyes with retinal detachment complicated with proliferative vitreoretinopathy compared with the uncomplicated
Název v anglickém jazyce
Defining the seriousness of proliferative vitreoretinopathy by aspiration of cytokines from the anterior chamber
Popis výsledku anglicky
Proliferative vitreoretinopathy is the major cause of retinal detachment surgery failure. Our prospective cohort study of 27 eyes aimed to determine intraocular levels of growth factors and cytokines in patients with retinal detachment with various degrees of severity of proliferative vitreoretinopathy using multiplex xMAP((R)) Technology. Patients & methods: The concentrations of 12 proangiogenic, antiangiogenic, inflammatory and neurotrophic factors were measured from 0.05-ml samples of intraocular fluid using multiplex xMAP Technology. The results were compared with levels of various factors, which were measured in samples from the control group of 31 eyes prior to senile cataract surgery. Results: The concentration of the MCP-1 cytokine was found to be higher in eyes with retinal detachment compared with the control group. The concentration of VEGF was found to be higher in eyes with retinal detachment complicated with proliferative vitreoretinopathy compared with the uncomplicated
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FF - ORL, oftalmologie, stomatologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
<a href="/cs/project/NS10251" target="_blank" >NS10251: Stanovení promotorů angiogeneze v nitrooční tekutině multiplexovou analýzou</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biomarkers in Medicine
ISSN
1752-0363
e-ISSN
—
Svazek periodika
7
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
9
Strana od-do
759-767
Kód UT WoS článku
000324474800016
EID výsledku v databázi Scopus
—