Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (>= 10 cm): A Retrospective Multicentric Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F16%3A10332348" target="_blank" >RIV/00669806:_____/16:10332348 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/16:10332348

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.clgc.2016.01.007" target="_blank" >http://dx.doi.org/10.1016/j.clgc.2016.01.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clgc.2016.01.007" target="_blank" >10.1016/j.clgc.2016.01.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (>= 10 cm): A Retrospective Multicentric Study

Popis výsledku v původním jazyce

One hundred sixteen patients who had a laparoscopic nephrectomy for big tumors were included. Conversion to open surgery was necessary in 20.7%. Hemorrhage occurred in 16.4%, resulting in open conversion in 62.5%. Intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery. Laparoscopic nephrectomy for tumors > 10 cm can be performed safely with comparable results to open surgery. Objective: Evaluate the feasibility of laparoscopic nephrectomy for big tumors. Material and Methods: Data from 116 patients were retrospectively collected from 16 tertiary centres. Clinical and operative parameters, tumor characteristics, pre- and postoperative parameters, and renal function before and after surgery were analyzed. Results: Mean age and body mass index were 61 years and 27.8 kg/m(2), respectively. Males represented 63.8% of patients, and 54.4% presented symptoms at diagnosis. Median tumor size was 11 cm, and 75% of the cases were performed by expert surgeons. Median operative time and blood loss were 180 minutes and 200 mL respectively. Conversion to open surgery was necessary in 20.7% of cases. Intraoperative complications related to massive hemorrhage occurred in 16.4% of patients, resulting in open conversion in 62.5%. Major postoperative complications occurred in only 10 patients (8.6%). In univariate analysis, intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery. Positive surgical margins occurred in 6 patients (5.2%). None of them presented a local recurrence. Predictive factors of recurrence or progression were lymph node invasion, metastases, and Furhman grade. Conclusion: Laparoscopic nephrectomy for tumors > 10 cm can be performed safely. Complication rate and positive surgical margins are similar to open surgery. In experienced hands, the benefit of a mini invasive surgery remains evident.

Název v anglickém jazyce

Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (>= 10 cm): A Retrospective Multicentric Study

Popis výsledku anglicky

One hundred sixteen patients who had a laparoscopic nephrectomy for big tumors were included. Conversion to open surgery was necessary in 20.7%. Hemorrhage occurred in 16.4%, resulting in open conversion in 62.5%. Intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery. Laparoscopic nephrectomy for tumors > 10 cm can be performed safely with comparable results to open surgery. Objective: Evaluate the feasibility of laparoscopic nephrectomy for big tumors. Material and Methods: Data from 116 patients were retrospectively collected from 16 tertiary centres. Clinical and operative parameters, tumor characteristics, pre- and postoperative parameters, and renal function before and after surgery were analyzed. Results: Mean age and body mass index were 61 years and 27.8 kg/m(2), respectively. Males represented 63.8% of patients, and 54.4% presented symptoms at diagnosis. Median tumor size was 11 cm, and 75% of the cases were performed by expert surgeons. Median operative time and blood loss were 180 minutes and 200 mL respectively. Conversion to open surgery was necessary in 20.7% of cases. Intraoperative complications related to massive hemorrhage occurred in 16.4% of patients, resulting in open conversion in 62.5%. Major postoperative complications occurred in only 10 patients (8.6%). In univariate analysis, intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery. Positive surgical margins occurred in 6 patients (5.2%). None of them presented a local recurrence. Predictive factors of recurrence or progression were lymph node invasion, metastases, and Furhman grade. Conclusion: Laparoscopic nephrectomy for tumors > 10 cm can be performed safely. Complication rate and positive surgical margins are similar to open surgery. In experienced hands, the benefit of a mini invasive surgery remains evident.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Genitourinary Cancer

ISSN

1558-7673

e-ISSN

—

Svazek periodika

14

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

"E335"-"E340"

Kód UT WoS článku

000380760500022

EID výsledku v databázi Scopus

2-s2.0-84957617329