Pseudo-"solid pseudopapillary neoplasms" of the testis: in reality Sertoli cell tumors-reply

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F19%3A10395933" target="_blank" >RIV/00669806:_____/19:10395933 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/19:10395933

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=L75VVzr5z7" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=L75VVzr5z7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.humpath.2018.07.034" target="_blank" >10.1016/j.humpath.2018.07.034</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Pseudo-"solid pseudopapillary neoplasms" of the testis: in reality Sertoli cell tumors-reply

Popis výsledku v původním jazyce

We would like to thank Drs Ulbright and Young for their comment on our articles about pancreatic analog of solid pseudopapillary neoplasm of the testis (11, in which we have describe d a total of 7 testicular tumors that have the morphologic features, immunohistochemical profile (positivity for Beta-catenin, cyclin D1, CD10, CD56, NSE, (often) synaptophysin; uniform negativity for inhibin, calretinin, SF-1, and chromogranin), and oncogenic somatic mutaiton in exon 3 of the CTNNB1 (Beta-catenin) gene identical to those seen in solid pseudopapillary neoplasms (SPNs) of the pancreas (2,3). In addition in a separate article, we have described 13 signet ring cell testicular tumors that have immunohistochemical profile and Beta-catenin mutations identical to those encountered in SPN of the pancreas (4). these 13 testicular tumor were hypothetically likened topancreatic SPN based on the fact that most pancreatic PSNs (20/22) in our files have a signet ring cell component. We acknowledged that it would need some time to recognize that these 136 signet ring cell tumors of the testis and SPN of the pancreas likely represet the same entity in different anatomic sites.

Název v anglickém jazyce

Pseudo-"solid pseudopapillary neoplasms" of the testis: in reality Sertoli cell tumors-reply

Popis výsledku anglicky

We would like to thank Drs Ulbright and Young for their comment on our articles about pancreatic analog of solid pseudopapillary neoplasm of the testis (11, in which we have describe d a total of 7 testicular tumors that have the morphologic features, immunohistochemical profile (positivity for Beta-catenin, cyclin D1, CD10, CD56, NSE, (often) synaptophysin; uniform negativity for inhibin, calretinin, SF-1, and chromogranin), and oncogenic somatic mutaiton in exon 3 of the CTNNB1 (Beta-catenin) gene identical to those seen in solid pseudopapillary neoplasms (SPNs) of the pancreas (2,3). In addition in a separate article, we have described 13 signet ring cell testicular tumors that have immunohistochemical profile and Beta-catenin mutations identical to those encountered in SPN of the pancreas (4). these 13 testicular tumor were hypothetically likened topancreatic SPN based on the fact that most pancreatic PSNs (20/22) in our files have a signet ring cell component. We acknowledged that it would need some time to recognize that these 136 signet ring cell tumors of the testis and SPN of the pancreas likely represet the same entity in different anatomic sites.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30109 - Pathology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Human Pathology

ISSN

0046-8177

e-ISSN

—

Svazek periodika

83

Číslo periodika v rámci svazku

January

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

230-232

Kód UT WoS článku

000459234800032

EID výsledku v databázi Scopus

2-s2.0-85060870404