PrEp Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F23%3A10452347" target="_blank" >RIV/00669806:_____/23:10452347 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/23:10452347

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=yJg3qH9F8Q" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=yJg3qH9F8Q</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/vaccines11010122" target="_blank" >10.3390/vaccines11010122</a>

Jazyk výsledku

angličtina

Název v původním jazyce

PrEp Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future

Popis výsledku v původním jazyce

With no expected vaccine for HIV in the near future, we aimed to define the currentsituation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central andEastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respondto a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%;95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily(40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was &lt;1-80%. Three major barriersfor access were lack of knowledge/awareness among people who are in need (59.1%), not beingreimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only foraccidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was availablein 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, ahuge gap exists between those who are in need of and those who can access PrEP. Prompt action isrequired to address the urgent need for PrEP scale-up in the CEE region.

Název v anglickém jazyce

PrEp Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future

Popis výsledku anglicky

With no expected vaccine for HIV in the near future, we aimed to define the currentsituation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central andEastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respondto a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%;95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily(40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was &lt;1-80%. Three major barriersfor access were lack of knowledge/awareness among people who are in need (59.1%), not beingreimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only foraccidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was availablein 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, ahuge gap exists between those who are in need of and those who can access PrEP. Prompt action isrequired to address the urgent need for PrEP scale-up in the CEE region.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Vaccines

ISSN

2076-393X

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

12

Strana od-do

1-12

Kód UT WoS článku

000941320000001

EID výsledku v databázi Scopus

2-s2.0-85146911661