Results of combined radiotherapy and hormonal treatment of prostate cancer patients with initial PSA value >40 ng/ml

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F12%3A00102799" target="_blank" >RIV/00843989:_____/12:00102799 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.rpor.2012.01.006" target="_blank" >http://dx.doi.org/10.1016/j.rpor.2012.01.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rpor.2012.01.006" target="_blank" >10.1016/j.rpor.2012.01.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Results of combined radiotherapy and hormonal treatment of prostate cancer patients with initial PSA value >40 ng/ml

Popis výsledku v původním jazyce

Aim: To evaluate the outcome of prostate cancer patients with initial PSA value >40ng/ml. Background: The outcome of prostate cancer patients with very high initial PSA value is not known and patients are frequently treated with palliative intent. We analyzed the outcome of radical combined hormonal treatment and radiotherapy in prostate cancer patients with initial PSA value >40ng/ml. Methods: Between January 2003 and December 2007 we treated, with curative intent, 56 patients with non-metastatic prostate cancer and initial PSA value >40 ng/ml. The treatment consisted of two months of neoadjuvant hormonal treatment (LHRH analog), radical radiotherapy (68-78 Gy, conformal technique) and an optional two-year adjuvant hormonal treatment. Results: The median time of follow up was 61 months. 5-Year overall survival was 90%. 5-Year biochemical disease free survival was 62%. T stage, Gleason score, PSA value, and radiotherapy dose did not significantly influence the outcome. Late genitourina

Název v anglickém jazyce

Results of combined radiotherapy and hormonal treatment of prostate cancer patients with initial PSA value >40 ng/ml

Popis výsledku anglicky

Aim: To evaluate the outcome of prostate cancer patients with initial PSA value >40ng/ml. Background: The outcome of prostate cancer patients with very high initial PSA value is not known and patients are frequently treated with palliative intent. We analyzed the outcome of radical combined hormonal treatment and radiotherapy in prostate cancer patients with initial PSA value >40ng/ml. Methods: Between January 2003 and December 2007 we treated, with curative intent, 56 patients with non-metastatic prostate cancer and initial PSA value >40 ng/ml. The treatment consisted of two months of neoadjuvant hormonal treatment (LHRH analog), radical radiotherapy (68-78 Gy, conformal technique) and an optional two-year adjuvant hormonal treatment. Results: The median time of follow up was 61 months. 5-Year overall survival was 90%. 5-Year biochemical disease free survival was 62%. T stage, Gleason score, PSA value, and radiotherapy dose did not significantly influence the outcome. Late genitourina

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Reports of practical oncology and radiotherapy

ISSN

1507-1367

e-ISSN

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Svazek periodika

17

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

6

Strana od-do

79-84

Kód UT WoS článku

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EID výsledku v databázi Scopus

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