Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0103887" target="_blank" >RIV/00843989:_____/14:E0103887 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1097/IGC.0000000000000043" target="_blank" >http://dx.doi.org/10.1097/IGC.0000000000000043</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/IGC.0000000000000043" target="_blank" >10.1097/IGC.0000000000000043</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node

Popis výsledku v původním jazyce

OBJECTIVE: In this study, we aimed to describe the value of pelvic lymph node dissection (LND) after sentinel lymph node (SN) biopsy in early-stage cervical cancer. METHODS: We performed a retrospective multicenter cohort study in 8 gynecological oncology departments. In total, 645 women with International Federation of Gynecology and Obstetrics stage IA to IIB cervical cancer of squamous, adeno, or adenosquamous histologic type who underwent SN biopsy followed by pelvic LND were enrolled in this study.Radioisotope tracers and blue dye were used to localize the sentinel node, and pathologic ultrastaging was performed. RESULTS: Among the patients with low-volume disease (micrometastases and isolated tumor cells) in the sentinel node, the overall survival was significantly better (P = 0.046) if more than 16 non-SNs were removed. No such significant difference in survival was detected in patients with negative or macrometastatic sentinel nodes. CONCLUSIONS: Our findings indicate that in

Název v anglickém jazyce

Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node

Popis výsledku anglicky

OBJECTIVE: In this study, we aimed to describe the value of pelvic lymph node dissection (LND) after sentinel lymph node (SN) biopsy in early-stage cervical cancer. METHODS: We performed a retrospective multicenter cohort study in 8 gynecological oncology departments. In total, 645 women with International Federation of Gynecology and Obstetrics stage IA to IIB cervical cancer of squamous, adeno, or adenosquamous histologic type who underwent SN biopsy followed by pelvic LND were enrolled in this study.Radioisotope tracers and blue dye were used to localize the sentinel node, and pathologic ultrastaging was performed. RESULTS: Among the patients with low-volume disease (micrometastases and isolated tumor cells) in the sentinel node, the overall survival was significantly better (P = 0.046) if more than 16 non-SNs were removed. No such significant difference in survival was detected in patients with negative or macrometastatic sentinel nodes. CONCLUSIONS: Our findings indicate that in

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of gynecological cancer

ISSN

1048-891X

e-ISSN

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Svazek periodika

24

Číslo periodika v rámci svazku

n. 2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

"p. 303-311"

Kód UT WoS článku

000336489200020

EID výsledku v databázi Scopus

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