Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F15%3AE0105021" target="_blank" >RIV/00843989:_____/15:E0105021 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/alr.21560" target="_blank" >http://dx.doi.org/10.1002/alr.21560</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/alr.21560" target="_blank" >10.1002/alr.21560</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux

Popis výsledku v původním jazyce

Background: The aim of this study was to determine the severity of extraesophageal reflux (EER) in patients with various degrees of chronic rhinosinusitis (CRS), and particularly in patients with simultaneous bronchial asthma. Methods:Patients with different severity of CRS were invited to participate in the study. Group I consisted of patients with CRS without nasal polyps or bronchial asthma; group II consisted of patients with CRS with nasal polyps but without bronchial asthma; group III consisted of patients with CRS with nasal polyps and bronchial asthma. The age, gender, Reflux Symptom Index, severity of EER evaluated using the Restech system, and number of previous functional endoscopic sinus surgeries (FESSs) were compared between groups. Results: A total of 90 patients (30 in each group) were recruited for the study. Pathological EER was significantly often present in group III when compared with group I and group II in all parameters analyzed (RYAN score, number of EER episodes, total percentage of time below pH 5.5). Furthermore, patients from group III had undergone more surgeries in the past. Conclusion: Patients with CRS with nasal polyps and simultaneous bronchial asthma suffer from significant EER. Antireflux therapy can be recommended for these patients. However, the effect has to be confirmed in further studies.

Název v anglickém jazyce

Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux

Popis výsledku anglicky

Background: The aim of this study was to determine the severity of extraesophageal reflux (EER) in patients with various degrees of chronic rhinosinusitis (CRS), and particularly in patients with simultaneous bronchial asthma. Methods:Patients with different severity of CRS were invited to participate in the study. Group I consisted of patients with CRS without nasal polyps or bronchial asthma; group II consisted of patients with CRS with nasal polyps but without bronchial asthma; group III consisted of patients with CRS with nasal polyps and bronchial asthma. The age, gender, Reflux Symptom Index, severity of EER evaluated using the Restech system, and number of previous functional endoscopic sinus surgeries (FESSs) were compared between groups. Results: A total of 90 patients (30 in each group) were recruited for the study. Pathological EER was significantly often present in group III when compared with group I and group II in all parameters analyzed (RYAN score, number of EER episodes, total percentage of time below pH 5.5). Furthermore, patients from group III had undergone more surgeries in the past. Conclusion: Patients with CRS with nasal polyps and simultaneous bronchial asthma suffer from significant EER. Antireflux therapy can be recommended for these patients. However, the effect has to be confirmed in further studies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

—

Projekt

<a href="/cs/project/NT13500" target="_blank" >NT13500: Diagnostika extraezofageálního refluxu pomocí systému Restech u pacientů s chronickou rinosinusitidou</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International forum of allergy & rhinology

ISSN

2042-6976

e-ISSN

—

Svazek periodika

5

Číslo periodika v rámci svazku

n. 10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

"p. 944-949"

Kód UT WoS článku

000363215400011

EID výsledku v databázi Scopus

—