Dexamethasone reduces the incidence of postoperative nausea and vomiting in children undergoing endoscopic adenoidectomy under general anesthesia without increasing the risk of postoperative hemorrhage

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F18%3AE0107329" target="_blank" >RIV/00843989:_____/18:E0107329 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.medscimonit.com/abstract/index/idArt/911231" target="_blank" >https://www.medscimonit.com/abstract/index/idArt/911231</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12659/MSM.911231" target="_blank" >10.12659/MSM.911231</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Dexamethasone reduces the incidence of postoperative nausea and vomiting in children undergoing endoscopic adenoidectomy under general anesthesia without increasing the risk of postoperative hemorrhage

Popis výsledku v původním jazyce

BACKGROUND: Postoperative nausea and vomiting (PONV) is a common complication of pediatric anesthesia, but the overall incidence of PONV in patients undergoing adenoidectomy is unknown. The aim of this controlled study was to compare the effect of dexamethasone administration with placebo to reduce PONV in children undergoing endoscopic adenoidectomy under general anesthesia. MATERIAL AND METHODS: A randomized placebo-controlled study included 118 pediatric patients who underwent elective endoscopic adenoidectomy under general anesthesia. A dexamethasone-treated (0.15 mg/kg) group (Group D) (n=56) and a placebo group (Group C) (n=62) were randomly assigned. The incidence of nausea and vomiting was recorded on the day of surgery. Postoperative nausea was assessed according to illustrated Baxter Animated Retching Faces (BARF) scale. The Face, Legs, Activity, Cry, and Consolability (FLACC) scale (scores between 0–10) was used to assess pain. Follow-up was performed on the 14th postoperative day by a telephone call. RESULTS: Overall prevalence of postoperative nausea was 25% (30/118) and postoperative vomiting was 14% (17/118). In the first 24 hours following surgery, in Group D, the incidence of nausea and vomiting was 13% and 7%, respectively; in Group C, without pharmacological prophylaxis, the incidence of postoperative nausea and vomiting was 37%, and 21%, respectively. CONCLUSIONS: A prospective controlled study in children undergoing endoscopic adenoidectomy under general anesthesia showed that dexamethasone (0.15 mg/kg) significantly reduced the incidence of PONV without increasing the risk of postoperative hemorrhage. Dexamethasone is a safe method for the prevention of PONV that may be recommended in pediatric anesthesiology.

Název v anglickém jazyce

Dexamethasone reduces the incidence of postoperative nausea and vomiting in children undergoing endoscopic adenoidectomy under general anesthesia without increasing the risk of postoperative hemorrhage

Popis výsledku anglicky

BACKGROUND: Postoperative nausea and vomiting (PONV) is a common complication of pediatric anesthesia, but the overall incidence of PONV in patients undergoing adenoidectomy is unknown. The aim of this controlled study was to compare the effect of dexamethasone administration with placebo to reduce PONV in children undergoing endoscopic adenoidectomy under general anesthesia. MATERIAL AND METHODS: A randomized placebo-controlled study included 118 pediatric patients who underwent elective endoscopic adenoidectomy under general anesthesia. A dexamethasone-treated (0.15 mg/kg) group (Group D) (n=56) and a placebo group (Group C) (n=62) were randomly assigned. The incidence of nausea and vomiting was recorded on the day of surgery. Postoperative nausea was assessed according to illustrated Baxter Animated Retching Faces (BARF) scale. The Face, Legs, Activity, Cry, and Consolability (FLACC) scale (scores between 0–10) was used to assess pain. Follow-up was performed on the 14th postoperative day by a telephone call. RESULTS: Overall prevalence of postoperative nausea was 25% (30/118) and postoperative vomiting was 14% (17/118). In the first 24 hours following surgery, in Group D, the incidence of nausea and vomiting was 13% and 7%, respectively; in Group C, without pharmacological prophylaxis, the incidence of postoperative nausea and vomiting was 37%, and 21%, respectively. CONCLUSIONS: A prospective controlled study in children undergoing endoscopic adenoidectomy under general anesthesia showed that dexamethasone (0.15 mg/kg) significantly reduced the incidence of PONV without increasing the risk of postoperative hemorrhage. Dexamethasone is a safe method for the prevention of PONV that may be recommended in pediatric anesthesiology.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30223 - Anaesthesiology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medical science monitor

ISSN

1234-1010

e-ISSN

1643-3750

Svazek periodika

24

Číslo periodika v rámci svazku

nov 22

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

8430-8438

Kód UT WoS článku

000451039400003

EID výsledku v databázi Scopus

2-s2.0-85057135772