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Effect duration of the initial course of peroneal electrical Transcutaneous NeuroModulation in patients with overactive bladder

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110302" target="_blank" >RIV/00843989:_____/23:E0110302 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/61988987:17110/23:A2402NE2 RIV/00216208:11130/23:10458584 RIV/00064203:_____/23:10458584

  • Výsledek na webu

    <a href="https://link.springer.com/article/10.1007/s00345-023-04394-z" target="_blank" >https://link.springer.com/article/10.1007/s00345-023-04394-z</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00345-023-04394-z" target="_blank" >10.1007/s00345-023-04394-z</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Effect duration of the initial course of peroneal electrical Transcutaneous NeuroModulation in patients with overactive bladder

  • Popis výsledku v původním jazyce

    Purpose: The aim of this prospective 12-month follow-up study is to evaluate the persistence of the treatment effect achieved during the initial course of peroneal electrical Transcutaneous NeuroModulation (peroneal eTNM®) in patients with overactive bladder (OAB). Methods: This study enrolled 21 female patients who participated in two previous clinical studies designed to assess the efficacy and safety of peroneal eTNM®. The patients were left without subsequent OAB treatment and were invited to attend regular follow-up visits every 3 months. The patient's request for additional treatment was considered an indicator of the withdrawal of the treatment effect of the initial course of peroneal eTNM®. The primary objective was the proportion of patients with persisting treatment effect at follow-up visit 12 months after initial course of peroneal eTNM®. Descriptive statistics are presented using median, correlation analyses were computed using a nonparametric Spearman correlation. Results: The proportion of patients with persistent therapeutic effect of the initial course of peroneal eTNM® was 76%, 76%, 62% and 48% at 3, 6, 9 and 12 months, respectively. There was a significant correlation between patient reported outcomes and the number of severe urgency episodes with or without urgency incontinence as reported by patients at each follow-up visit (p = 0.0017). Conclusion: The treatment effect achieved during the initial phase of peroneal eTNM® persists for at least 12 months in 48% of patients. It is likely that the duration of effects is dependent on the length of the initial therapy.

  • Název v anglickém jazyce

    Effect duration of the initial course of peroneal electrical Transcutaneous NeuroModulation in patients with overactive bladder

  • Popis výsledku anglicky

    Purpose: The aim of this prospective 12-month follow-up study is to evaluate the persistence of the treatment effect achieved during the initial course of peroneal electrical Transcutaneous NeuroModulation (peroneal eTNM®) in patients with overactive bladder (OAB). Methods: This study enrolled 21 female patients who participated in two previous clinical studies designed to assess the efficacy and safety of peroneal eTNM®. The patients were left without subsequent OAB treatment and were invited to attend regular follow-up visits every 3 months. The patient's request for additional treatment was considered an indicator of the withdrawal of the treatment effect of the initial course of peroneal eTNM®. The primary objective was the proportion of patients with persisting treatment effect at follow-up visit 12 months after initial course of peroneal eTNM®. Descriptive statistics are presented using median, correlation analyses were computed using a nonparametric Spearman correlation. Results: The proportion of patients with persistent therapeutic effect of the initial course of peroneal eTNM® was 76%, 76%, 62% and 48% at 3, 6, 9 and 12 months, respectively. There was a significant correlation between patient reported outcomes and the number of severe urgency episodes with or without urgency incontinence as reported by patients at each follow-up visit (p = 0.0017). Conclusion: The treatment effect achieved during the initial phase of peroneal eTNM® persists for at least 12 months in 48% of patients. It is likely that the duration of effects is dependent on the length of the initial therapy.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30217 - Urology and nephrology

Návaznosti výsledku

  • Projekt

  • Návaznosti

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Ostatní

  • Rok uplatnění

    2023

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    World journal of urology

  • ISSN

    0724-4983

  • e-ISSN

    1433-8726

  • Svazek periodika

    41

  • Číslo periodika v rámci svazku

    6

  • Stát vydavatele periodika

    DE - Spolková republika Německo

  • Počet stran výsledku

    6

  • Strana od-do

    1629-1634

  • Kód UT WoS článku

    000965128900001

  • EID výsledku v databázi Scopus

    2-s2.0-85151952090