Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0110801" target="_blank" >RIV/00843989:_____/24:E0110801 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00135314 RIV/61988987:17110/24:A2502NNU

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S2352556823001261?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2352556823001261?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.accpm.2023.101318" target="_blank" >10.1016/j.accpm.2023.101318</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial

Popis výsledku v původním jazyce

Objective: Emergence delirium (ED) is a postoperative complication in pediatric anesthesia characterized by a perception and psychomotor disorder, with a negative impact on postoperative recovery. As the use of inhalation anesthesia is associated with a higher incidence of ED, we investigated whether titrating the depth of general anesthesia with BIS monitor can reduce the incidence of ED. Design: Randomized, prospective, and double-blind. Setting: Patients undergoing endoscopic adenoidectomy under general anesthesia according to a uniform protocol. Patients: A total of 163 patients of both sexes aged 3-8 years were enrolled over 18 months. Interventions: Immediately after the induction of general anesthesia, a bispectral index (BIS) electrode was placed on the patient's forehead. In the study group, the depth of general anesthesia was monitored with the aim of achieving BIS values of 40-60. In the control group, the dose of sevoflurane was determined by the anaesthesiologist based on MAC (minimum alveolar concentration) and the end-tidal concentration. Measurements: The primary objective was to compare the occurrence of ED during the PACU (post-anesthesia care unit) stay in both arms of the study. The secondary objective was to determine the PAED score at 10 and 30 min in the PACU and the need for rescue treatment of ED. Main results: 86 children were randomized in the intervention group and 77 children in the control group. During the entire PACU stay, 23.3% (38/163) of patients developed ED with PAED score >10: 35.1% (27/77) in the control group and 12.8% (11/86) in the intervention group (p = 0.001). Lower PAED scores were also found in the intervention group at 10 (p < 0.001) and 30 (p < 0.001) minutes compared to the control group. The need for rescue treatment did not differ between groups (p = 0.067). Conclusion: Individualization of the depth of general anesthesia with BIS monitoring is an effective method of preventing ED in children.

Název v anglickém jazyce

Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial

Popis výsledku anglicky

Objective: Emergence delirium (ED) is a postoperative complication in pediatric anesthesia characterized by a perception and psychomotor disorder, with a negative impact on postoperative recovery. As the use of inhalation anesthesia is associated with a higher incidence of ED, we investigated whether titrating the depth of general anesthesia with BIS monitor can reduce the incidence of ED. Design: Randomized, prospective, and double-blind. Setting: Patients undergoing endoscopic adenoidectomy under general anesthesia according to a uniform protocol. Patients: A total of 163 patients of both sexes aged 3-8 years were enrolled over 18 months. Interventions: Immediately after the induction of general anesthesia, a bispectral index (BIS) electrode was placed on the patient's forehead. In the study group, the depth of general anesthesia was monitored with the aim of achieving BIS values of 40-60. In the control group, the dose of sevoflurane was determined by the anaesthesiologist based on MAC (minimum alveolar concentration) and the end-tidal concentration. Measurements: The primary objective was to compare the occurrence of ED during the PACU (post-anesthesia care unit) stay in both arms of the study. The secondary objective was to determine the PAED score at 10 and 30 min in the PACU and the need for rescue treatment of ED. Main results: 86 children were randomized in the intervention group and 77 children in the control group. During the entire PACU stay, 23.3% (38/163) of patients developed ED with PAED score >10: 35.1% (27/77) in the control group and 12.8% (11/86) in the intervention group (p = 0.001). Lower PAED scores were also found in the intervention group at 10 (p < 0.001) and 30 (p < 0.001) minutes compared to the control group. The need for rescue treatment did not differ between groups (p = 0.067). Conclusion: Individualization of the depth of general anesthesia with BIS monitoring is an effective method of preventing ED in children.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30223 - Anaesthesiology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Anaesthesia critical care & pain medicine

ISSN

2352-5568

e-ISSN

2352-5568

Svazek periodika

43

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

6

Strana od-do

1-6

Kód UT WoS článku

001124655500001

EID výsledku v databázi Scopus

2-s2.0-85177813484