Enhancing ROP plus form diagnosis: An automatic blood vessel segmentation approach for newborn fundus images

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0111539" target="_blank" >RIV/00843989:_____/24:E0111539 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S2590123024013094?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2590123024013094?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rineng.2024.103054" target="_blank" >10.1016/j.rineng.2024.103054</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Enhancing ROP plus form diagnosis: An automatic blood vessel segmentation approach for newborn fundus images

Popis výsledku v původním jazyce

Background: ROP Plus Form is an eye disease that can lead to blindness, and diagnosing it requires medical experts to manually examine the retinal condition. This task is challenging due to its subjective nature and poor image quality. Therefore, developing automatic tools for Retinal Blood Vessel Segmentation in fundus images could assist healthcare experts in diagnosing, monitoring, and prognosing the disease. Objective: This study focuses on developing a novel pipeline for automatically segmenting retinal blood vessels. The main requirements are that it can correctly identify the blood vessels in fundus images and perform well on different systems used for newborn evaluation. Methods: The pipeline uses different methods, including CIELAB Enhancement, Background Normalization, BellShaped Gaussian Matched Filtering, Modified Top-Hat operation, and a combination of vesselness filtering composed of Frangi and Jerman Filters. The segmentation is done by determining a threshold using the Triangle Threshold algorithm. A novel filter is also proposed to remove the Optical Disc artifacts from the primary segmentation based on the Circular Hough Transform. The segmentation pipeline is combined with different pretrained Convolution Neural Network architectures to evaluate its automatic classification capabilities. Results: The pipeline was tested with newborn fundus images acquired with Clarity RetCam3 and Phoenix ICON systems. The results were compared against annotations from three ophthalmologic experts. Clarity RetCam3 images achieved an accuracy of 0.94, specificity of 0.95, and sensitivity of 0.81, while Phoenix ICON images achieved an accuracy of 0.94, specificity of 0.97, and sensitivity of 0.83. The pipeline was also tested for the DRIVE Database, achieving an accuracy of 0.95, specificity of 0.97, and sensitivity of 0.82. For the classification task, the best results were achieved with the DenseNet121 architecture with an accuracy of 0.946. Conclusion: The segm...

Název v anglickém jazyce

Enhancing ROP plus form diagnosis: An automatic blood vessel segmentation approach for newborn fundus images

Popis výsledku anglicky

Background: ROP Plus Form is an eye disease that can lead to blindness, and diagnosing it requires medical experts to manually examine the retinal condition. This task is challenging due to its subjective nature and poor image quality. Therefore, developing automatic tools for Retinal Blood Vessel Segmentation in fundus images could assist healthcare experts in diagnosing, monitoring, and prognosing the disease. Objective: This study focuses on developing a novel pipeline for automatically segmenting retinal blood vessels. The main requirements are that it can correctly identify the blood vessels in fundus images and perform well on different systems used for newborn evaluation. Methods: The pipeline uses different methods, including CIELAB Enhancement, Background Normalization, BellShaped Gaussian Matched Filtering, Modified Top-Hat operation, and a combination of vesselness filtering composed of Frangi and Jerman Filters. The segmentation is done by determining a threshold using the Triangle Threshold algorithm. A novel filter is also proposed to remove the Optical Disc artifacts from the primary segmentation based on the Circular Hough Transform. The segmentation pipeline is combined with different pretrained Convolution Neural Network architectures to evaluate its automatic classification capabilities. Results: The pipeline was tested with newborn fundus images acquired with Clarity RetCam3 and Phoenix ICON systems. The results were compared against annotations from three ophthalmologic experts. Clarity RetCam3 images achieved an accuracy of 0.94, specificity of 0.95, and sensitivity of 0.81, while Phoenix ICON images achieved an accuracy of 0.94, specificity of 0.97, and sensitivity of 0.83. The pipeline was also tested for the DRIVE Database, achieving an accuracy of 0.95, specificity of 0.97, and sensitivity of 0.82. For the classification task, the best results were achieved with the DenseNet121 architecture with an accuracy of 0.946. Conclusion: The segm...

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Results in engineering

ISSN

2590-1230

e-ISSN

2590-1230

Svazek periodika

24

Číslo periodika v rámci svazku

article 103054

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

17

Strana od-do

1-17

Kód UT WoS článku

001334066600001

EID výsledku v databázi Scopus

2-s2.0-85205763616