Visual outcomes in patients with meningiomas compressing optic nerve

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0111830" target="_blank" >RIV/00843989:_____/25:E0111830 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/25:10159347

Výsledek na webu

<a href="https://doi.org/10.3389/fneur.2025.1606661" target="_blank" >https://doi.org/10.3389/fneur.2025.1606661</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fneur.2025.1606661" target="_blank" >10.3389/fneur.2025.1606661</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Visual outcomes in patients with meningiomas compressing optic nerve

Popis výsledku v původním jazyce

Background: Meningiomas compressing the optic nerve can lead to progressive visual loss due to the nerve's complex intraorbital, intracanalicular, and intracranial anatomy. Although observation, radiation, and surgical decompression are available, optimal strategies for preserving vision remain controversial. This study retrospectively evaluates the impact of surgical intervention on visual recovery in patients with optic nerve-compressing meningiomas to refine patient selection and treatment strategies. Methods: A retrospective review was conducted on medical records from the Neurosurgical Clinic at Olomouc University Hospital for patients undergoing surgical treatment for meningiomas near the optic nerve from 2015 to 2023. Inclusion criteria required high-quality preoperative and postoperative MRI, complete ophthalmic records, and a minimum one-year follow-up. Data on demographics, tumor characteristics (size, location, and relationship with the optic nerve), and visual function (acuity and field) were collected. Tumors were categorized by size and degree of optic nerve involvement, and visual outcomes were assessed pre- and postoperatively. Results: Seventy-nine patients (66 females, 13 males; mean age 58) met inclusion criteria. A longer duration of visual impairment correlated with more severe preoperative vision loss. Although postoperative visual function did not significantly correlate with tumor size, location, or duration of preoperative symptoms, patients with shorter impairment durations demonstrated better postoperative recovery. Conclusion: The duration of preoperative visual impairment is a critical predictor of visual outcomes, supporting early surgical intervention for optic nerve-compressing meningiomas. While tumor size and location did not directly influence recovery, further investigation into tumor-anatomy relationships is warranted to optimize visual prognosis.

Název v anglickém jazyce

Visual outcomes in patients with meningiomas compressing optic nerve

Popis výsledku anglicky

Background: Meningiomas compressing the optic nerve can lead to progressive visual loss due to the nerve's complex intraorbital, intracanalicular, and intracranial anatomy. Although observation, radiation, and surgical decompression are available, optimal strategies for preserving vision remain controversial. This study retrospectively evaluates the impact of surgical intervention on visual recovery in patients with optic nerve-compressing meningiomas to refine patient selection and treatment strategies. Methods: A retrospective review was conducted on medical records from the Neurosurgical Clinic at Olomouc University Hospital for patients undergoing surgical treatment for meningiomas near the optic nerve from 2015 to 2023. Inclusion criteria required high-quality preoperative and postoperative MRI, complete ophthalmic records, and a minimum one-year follow-up. Data on demographics, tumor characteristics (size, location, and relationship with the optic nerve), and visual function (acuity and field) were collected. Tumors were categorized by size and degree of optic nerve involvement, and visual outcomes were assessed pre- and postoperatively. Results: Seventy-nine patients (66 females, 13 males; mean age 58) met inclusion criteria. A longer duration of visual impairment correlated with more severe preoperative vision loss. Although postoperative visual function did not significantly correlate with tumor size, location, or duration of preoperative symptoms, patients with shorter impairment durations demonstrated better postoperative recovery. Conclusion: The duration of preoperative visual impairment is a critical predictor of visual outcomes, supporting early surgical intervention for optic nerve-compressing meningiomas. While tumor size and location did not directly influence recovery, further investigation into tumor-anatomy relationships is warranted to optimize visual prognosis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in neurology

ISSN

1664-2295

e-ISSN

1664-2295

Svazek periodika

16

Číslo periodika v rámci svazku

article 1606661

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

7

Strana od-do

1-7

Kód UT WoS článku

001518128500001

EID výsledku v databázi Scopus

2-s2.0-105009345259