The potential of microRNAs in the context of sarcopenic obesity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0112141" target="_blank" >RIV/00843989:_____/25:E0112141 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/25:A2603COT

Výsledek na webu

<a href="https://www.biomed.cas.cz/physiolres/pdf/74/74_S65.pdf" target="_blank" >https://www.biomed.cas.cz/physiolres/pdf/74/74_S65.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33549/physiolres.935755" target="_blank" >10.33549/physiolres.935755</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The potential of microRNAs in the context of sarcopenic obesity

Popis výsledku v původním jazyce

Sarcopenic obesity (SO) is a complex pathological condition characterized by the simultaneous presence of excessive adipose tissue and the loss of muscle mass and strength. This combination leads to an increased risk of metabolic, cardiovascular, and functional complications. In recent years, there has been growing interest in the use of microRNAs (miRNA) as biomarkers capable of detecting early changes in body composition and predicting the progression of SO. MiRNAs are small noncoding RNA molecules that play a key role in regulating gene expression and cellular pathways related to inflammation, metabolism, and muscle trophism. This article summarizes current knowledge about miRNAs expression in patients with sarcopenic obesity, their regulatory functions, and their potential use in diagnostics and therapy.

Název v anglickém jazyce

The potential of microRNAs in the context of sarcopenic obesity

Popis výsledku anglicky

Sarcopenic obesity (SO) is a complex pathological condition characterized by the simultaneous presence of excessive adipose tissue and the loss of muscle mass and strength. This combination leads to an increased risk of metabolic, cardiovascular, and functional complications. In recent years, there has been growing interest in the use of microRNAs (miRNA) as biomarkers capable of detecting early changes in body composition and predicting the progression of SO. MiRNAs are small noncoding RNA molecules that play a key role in regulating gene expression and cellular pathways related to inflammation, metabolism, and muscle trophism. This article summarizes current knowledge about miRNAs expression in patients with sarcopenic obesity, their regulatory functions, and their potential use in diagnostics and therapy.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological research

ISSN

0862-8408

e-ISSN

1802-9973

Svazek periodika

74

Číslo periodika v rámci svazku

suppl.1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

1

Strana od-do

s65-s75

Kód UT WoS článku

001690902000005

EID výsledku v databázi Scopus

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