Physical properties of native hyaluronan solutions for preparation of nanofibres

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F25281844%3A_____%2F10%3A%230000017" target="_blank" >RIV/25281844:_____/10:#0000017 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.nanocon.eu/files/proceedings/nanocon_10/lists/papers/430.pdf" target="_blank" >http://www.nanocon.eu/files/proceedings/nanocon_10/lists/papers/430.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Physical properties of native hyaluronan solutions for preparation of nanofibres

Popis výsledku v původním jazyce

Hyaluronan is a high molecular weight unbranched glycosaminoglycan, composed of repeating disaccharides. Hyaluronan is naturally found in many tissues of the body, such as skin, cartilage, and the vitreous humour. It is therefore well suited to biomedical applications targeting these tissues. The preparation of hyaluronan nanofibres is based on electrospinning method of hyaluronan solutions with the appropriate physical properties. Because the viscosity is known as one of the most important parameter that influences the nanofibres formation, the effect of molecular weight, concentration of HA and used´solvent on apparent viscosity was studied. Also other solutions properties, such a surface tension and conductivity were measured. Prepared solutions were electrospinned and formation of nanofibres was observed. The best parameters of hyaluronan solutions were chosen. The hyaluronan nanofibres were prepared. Also the critical overlap concentration (c*) was determined for water solutions o

Název v anglickém jazyce

Physical properties of native hyaluronan solutions for preparation of nanofibres

Popis výsledku anglicky

Hyaluronan is a high molecular weight unbranched glycosaminoglycan, composed of repeating disaccharides. Hyaluronan is naturally found in many tissues of the body, such as skin, cartilage, and the vitreous humour. It is therefore well suited to biomedical applications targeting these tissues. The preparation of hyaluronan nanofibres is based on electrospinning method of hyaluronan solutions with the appropriate physical properties. Because the viscosity is known as one of the most important parameter that influences the nanofibres formation, the effect of molecular weight, concentration of HA and used´solvent on apparent viscosity was studied. Also other solutions properties, such a surface tension and conductivity were measured. Prepared solutions were electrospinned and formation of nanofibres was observed. The best parameters of hyaluronan solutions were chosen. The hyaluronan nanofibres were prepared. Also the critical overlap concentration (c*) was determined for water solutions o

Druh

D - Stať ve sborníku

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

<a href="/cs/project/FR-TI1%2F151" target="_blank" >FR-TI1/151: *Nové kryty ran na bázi nano- a mikro- nosičů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Nanocon 2010

ISBN

978-80-87294-18-5

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

84

Název nakladatele

Tanger spol. s.r.o.

Místo vydání

Olomouc

Místo konání akce

Olomouc

Datum konání akce

12. 10. 2010

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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