Epigenetic Regulation of Fungicide Resistance in Plant-Pathogenic Fungi

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26784246%3A_____%2F25%3AN0000004" target="_blank" >RIV/26784246:_____/25:N0000004 - isvavai.cz</a>

Výsledek na webu

<a href="https://bsppjournals.onlinelibrary.wiley.com/doi/epdf/10.1111/ppa.14126" target="_blank" >https://bsppjournals.onlinelibrary.wiley.com/doi/epdf/10.1111/ppa.14126</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/ppa.14126" target="_blank" >10.1111/ppa.14126</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Epigenetic Regulation of Fungicide Resistance in Plant-Pathogenic Fungi

Popis výsledku v původním jazyce

Fungicides have been successfully used to control plant-pathogenic fungi in agriculture, but their continuous use has led to resistance developing against all significant fungicide modes of action worldwide. Notably, Phytophthora, Fusarium and Verticillium are the most troublesome plant pathogens with regard to developing fungicide resistance. In fungi, epigenetic mechanisms play critical roles by increasing their stress-adaptive potential in rapidly changing environments. These mechanisms involve alterations in the expression of genetic elements without changes in the DNA sequence. The role of epigenetic mechanisms in contributing to survival and fitness under various stresses is not well documented in fungi. Studies have shown differential expression of DNA methyltransferases, histone methyltransferases and DNA demethylases in response to fungicides; however, further research is needed. Exploring how these epigenetic processes affect gene expression patterns in fungi subjected to recurrent fungicide selection is crucial. Therefore, this mini-review will focus on the potential contributions of epigenetic mechanisms to the adaptive responses of plant pathogens to fungicide stress. A better understanding of these epigenetic changes will enhance our knowledge of fungicide resistance evolution in plant pathogens, potentially leading to the development of fungicides with novel targets.

Název v anglickém jazyce

Epigenetic Regulation of Fungicide Resistance in Plant-Pathogenic Fungi

Popis výsledku anglicky

Fungicides have been successfully used to control plant-pathogenic fungi in agriculture, but their continuous use has led to resistance developing against all significant fungicide modes of action worldwide. Notably, Phytophthora, Fusarium and Verticillium are the most troublesome plant pathogens with regard to developing fungicide resistance. In fungi, epigenetic mechanisms play critical roles by increasing their stress-adaptive potential in rapidly changing environments. These mechanisms involve alterations in the expression of genetic elements without changes in the DNA sequence. The role of epigenetic mechanisms in contributing to survival and fitness under various stresses is not well documented in fungi. Studies have shown differential expression of DNA methyltransferases, histone methyltransferases and DNA demethylases in response to fungicides; however, further research is needed. Exploring how these epigenetic processes affect gene expression patterns in fungi subjected to recurrent fungicide selection is crucial. Therefore, this mini-review will focus on the potential contributions of epigenetic mechanisms to the adaptive responses of plant pathogens to fungicide stress. A better understanding of these epigenetic changes will enhance our knowledge of fungicide resistance evolution in plant pathogens, potentially leading to the development of fungicides with novel targets.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Plant Pathology

ISSN

0032-0862

e-ISSN

1365-3059

Svazek periodika

74

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

1495–1503

Kód UT WoS článku

001498535800001

EID výsledku v databázi Scopus

2-s2.0-105006800013