Owerviev pf the most common untowards reactions to transfusion

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27283933%3A_____%2F17%3A00005437" target="_blank" >RIV/27283933:_____/17:00005437 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Owerviev pf the most common untowards reactions to transfusion

Popis výsledku v původním jazyce

Transfusion reactions are a diverse group of adverse reactions to transfusion that usually present during or after transfusion. Detection, transfusion. Detection, collection and analysis of information of adverse transfusion events and reactions are the difficult part of haemovigilance. A definition of adverse events, appropriate legislation and standards, reporting system (definitions of data collected, forms), analysis and feedback are needed for the system to function. The methodological base was established by the Guide on the Preparation, Use and Quality Assurance of Blood Components in 1995, the legislation base in the Directive 2002/98/EC. All adverse transfusion events can be classified as either as incidents or complications. Incidents are deviations from standard operating procedure or hospital policy during the transfusion proces. If not disclosed they could cause injury or death of recipient of transfusion. Near-miss events are recognised before transfusion starts, complete incidents (transfusion errors) are recognised during transfusion. Preventive actions should be undertaken in the case of near misses, whereas corrective as well as preventive actions shouold be carried out in the event of transfusion errors. The education of staff, process control and organization provisions are very important to minimize the risk of transfusion. Somplications are adverse reactions to or adverse effects of the transfused blood components. The complications can be categorized by mechanism, causes, symptoms, time of occurence, consenquences, and other categories. The EHN Working Party categorized adverse events in four categories in 2004: 1) transfusion - transmitted infections, 2) immune complications of transfusion, 3) cardiovascular and metabolic complications and 4) previously unknown complications of transfusion. Many of the complicaations are caused by the leucocytes present in the blood components. The severity of reactions can be graded by the standard system as grade 1-4. Moreower, a simplification of the imputability of reaction to transfusion is proposed.

Název v anglickém jazyce

Owerviev pf the most common untowards reactions to transfusion

Popis výsledku anglicky

Transfusion reactions are a diverse group of adverse reactions to transfusion that usually present during or after transfusion. Detection, transfusion. Detection, collection and analysis of information of adverse transfusion events and reactions are the difficult part of haemovigilance. A definition of adverse events, appropriate legislation and standards, reporting system (definitions of data collected, forms), analysis and feedback are needed for the system to function. The methodological base was established by the Guide on the Preparation, Use and Quality Assurance of Blood Components in 1995, the legislation base in the Directive 2002/98/EC. All adverse transfusion events can be classified as either as incidents or complications. Incidents are deviations from standard operating procedure or hospital policy during the transfusion proces. If not disclosed they could cause injury or death of recipient of transfusion. Near-miss events are recognised before transfusion starts, complete incidents (transfusion errors) are recognised during transfusion. Preventive actions should be undertaken in the case of near misses, whereas corrective as well as preventive actions shouold be carried out in the event of transfusion errors. The education of staff, process control and organization provisions are very important to minimize the risk of transfusion. Somplications are adverse reactions to or adverse effects of the transfused blood components. The complications can be categorized by mechanism, causes, symptoms, time of occurence, consenquences, and other categories. The EHN Working Party categorized adverse events in four categories in 2004: 1) transfusion - transmitted infections, 2) immune complications of transfusion, 3) cardiovascular and metabolic complications and 4) previously unknown complications of transfusion. Many of the complicaations are caused by the leucocytes present in the blood components. The severity of reactions can be graded by the standard system as grade 1-4. Moreower, a simplification of the imputability of reaction to transfusion is proposed.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

30230 - Other clinical medicine subjects

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů