Outcomes of Extended Pelvic Resections Involving Pelvic Nerves, Bones, and External Iliac Vessels, Performed with Curative Intent

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F17%3AN0000013" target="_blank" >RIV/27661989:_____/17:N0000013 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1048891X24191025" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1048891X24191025</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Outcomes of Extended Pelvic Resections Involving Pelvic Nerves, Bones, and External Iliac Vessels, Performed with Curative Intent

Popis výsledku v původním jazyce

Aims Pelvic exenteration (PE) offers a chance of 40–60% for long-term survival to selected patients with recurrent pelvic malignancies and no other curative alternative. Traditionally, the involvement of large vessels, nerves, and pelvic bones are considered contraindications. The aim of the paper is to present the outcome of the procedures performed with curative intent that go beyond the traditional limits of PE. Method Extended pelvic resections (EPR) were defined as procedures that included the resection of large pelvic nerves, external and common iliac vessels, and pelvic bones. Results EPR were performed in 20 patients with the recurrence of gynecological malignant tumours between 2011–2017. The spectrum of procedures comprised nerve resections in 18, bone resection in 5, and large vessel resection in 6 patients. No patient died of complications, but postoperative complications occurred in 12 patients, 9 of which required re-operation. Bone resection was not associated with any specific morbidity. Two cases of vascular resection required femoro-femoral artery bypass. Resection of large nerves caused functional loss and loss of sensation corresponding to individual nerve injury. Within the median follow-up of 18 months, 6 patients died of disease progression, 1 died of another cause, 2 are alive with disease, and 11 are without evidence of disease. Conclusion EPR is associated with specific short- and long-term morbidity; it is, however, feasible. The involvement of large vessels, nerves and bones do not represent an absolute contraindication for surgery in selected cases with pelvic recurrence.

Název v anglickém jazyce

Outcomes of Extended Pelvic Resections Involving Pelvic Nerves, Bones, and External Iliac Vessels, Performed with Curative Intent

Popis výsledku anglicky

Aims Pelvic exenteration (PE) offers a chance of 40–60% for long-term survival to selected patients with recurrent pelvic malignancies and no other curative alternative. Traditionally, the involvement of large vessels, nerves, and pelvic bones are considered contraindications. The aim of the paper is to present the outcome of the procedures performed with curative intent that go beyond the traditional limits of PE. Method Extended pelvic resections (EPR) were defined as procedures that included the resection of large pelvic nerves, external and common iliac vessels, and pelvic bones. Results EPR were performed in 20 patients with the recurrence of gynecological malignant tumours between 2011–2017. The spectrum of procedures comprised nerve resections in 18, bone resection in 5, and large vessel resection in 6 patients. No patient died of complications, but postoperative complications occurred in 12 patients, 9 of which required re-operation. Bone resection was not associated with any specific morbidity. Two cases of vascular resection required femoro-femoral artery bypass. Resection of large nerves caused functional loss and loss of sensation corresponding to individual nerve injury. Within the median follow-up of 18 months, 6 patients died of disease progression, 1 died of another cause, 2 are alive with disease, and 11 are without evidence of disease. Conclusion EPR is associated with specific short- and long-term morbidity; it is, however, feasible. The involvement of large vessels, nerves and bones do not represent an absolute contraindication for surgery in selected cases with pelvic recurrence.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Gynecological Cancer

ISSN

1048-891X

e-ISSN

1525-1438

Svazek periodika

27

Číslo periodika v rámci svazku

Supplement 4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

725-725

Kód UT WoS článku

000423235202220

EID výsledku v databázi Scopus

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