MAGNETIC RESONANCE IMAGING OR EXPERT ULTRASOUND IN PREOPERATIVE LOCAL STAGING OF PATIENTS WITH EARLY-STAGE CERVICAL CANCER: FINAL RESULTS OF THE SENTIX PROSPECTIVE, SINGLEARM, INTERNATIONAL TRIAL (CEEGOG CX-01; ENGOTCX2)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F23%3A10003406" target="_blank" >RIV/27661989:_____/23:10003406 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1048891X25003810" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1048891X25003810</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/ijgc-2023-ESGO.4" target="_blank" >10.1136/ijgc-2023-ESGO.4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

MAGNETIC RESONANCE IMAGING OR EXPERT ULTRASOUND IN PREOPERATIVE LOCAL STAGING OF PATIENTS WITH EARLY-STAGE CERVICAL CANCER: FINAL RESULTS OF THE SENTIX PROSPECTIVE, SINGLEARM, INTERNATIONAL TRIAL (CEEGOG CX-01; ENGOTCX2)

Popis výsledku v původním jazyce

SENTIX is a prospective, international, single‑arm study evaluating sentinel lymph node biopsy without pelvic lymph node dissection in patients with early‑stage cervical cancer. This presentation assesses the sensitivity of magnetic resonance imaging (MRI) and expert ultrasound (EUS) in preoperative clinical staging. A total of 690 eligible patients (FIGO 2018 stages 1A1/LVSI+ to 1B2) were enrolled. MRI was used in 46.7% and EUS in 43.1% of cases. Histopathology revealed previously unrecognized parametrial involvement in 3.8% of patients and sentinel lymph node metastasis in 9.9%. MRI and EUS demonstrated comparable sensitivity for tumour size assessment, detection of parametrial invasion, and identification of macrometastatic nodal disease. Combining both imaging modalities did not improve diagnostic performance. The findings confirm that MRI and EUS offer similar accuracy for preoperative staging of cervical cancer.

Název v anglickém jazyce

MAGNETIC RESONANCE IMAGING OR EXPERT ULTRASOUND IN PREOPERATIVE LOCAL STAGING OF PATIENTS WITH EARLY-STAGE CERVICAL CANCER: FINAL RESULTS OF THE SENTIX PROSPECTIVE, SINGLEARM, INTERNATIONAL TRIAL (CEEGOG CX-01; ENGOTCX2)

Popis výsledku anglicky

SENTIX is a prospective, international, single‑arm study evaluating sentinel lymph node biopsy without pelvic lymph node dissection in patients with early‑stage cervical cancer. This presentation assesses the sensitivity of magnetic resonance imaging (MRI) and expert ultrasound (EUS) in preoperative clinical staging. A total of 690 eligible patients (FIGO 2018 stages 1A1/LVSI+ to 1B2) were enrolled. MRI was used in 46.7% and EUS in 43.1% of cases. Histopathology revealed previously unrecognized parametrial involvement in 3.8% of patients and sentinel lymph node metastasis in 9.9%. MRI and EUS demonstrated comparable sensitivity for tumour size assessment, detection of parametrial invasion, and identification of macrometastatic nodal disease. Combining both imaging modalities did not improve diagnostic performance. The findings confirm that MRI and EUS offer similar accuracy for preoperative staging of cervical cancer.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Gynecological Cancer

ISSN

1048-891X

e-ISSN

1525-1438

Svazek periodika

33

Číslo periodika v rámci svazku

Suppl.ement 3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

"A2"-"A3"

Kód UT WoS článku

001264297900005

EID výsledku v databázi Scopus

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