Separation of phenylacetic acid from fermentation broth by bipolar electrodialysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F28676092%3A_____%2F18%3AN0000071" target="_blank" >RIV/28676092:_____/18:N0000071 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.czemp.cz/cs/protected-node?destination=node/1795&back=http%253A%252F%252Fwww.czemp.cz%252Fcs&protected_page=1795" target="_blank" >http://www.czemp.cz/cs/protected-node?destination=node/1795&back=http%253A%252F%252Fwww.czemp.cz%252Fcs&protected_page=1795</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Separation of phenylacetic acid from fermentation broth by bipolar electrodialysis

Popis výsledku v původním jazyce

The main aim of this work was separation of phenylacetic acid from model solution of fermentation broth by electrodialysis using bipolar membranes. Phenylacetic acid has wide variety of use in pharmaceutical (production of ẞ-lactam, analgesics, etc.), biotechnological and also in perfume industry (honey-like odor). In recent years, a lot of focus was aimed at biotechnological production of organic acids. Thanks to biotechnological production, such product can be labelled as natural according to EU legislation, which affects the product price on the market. However, downstream processing of the final product after bioproduction is often time-consuming and costly. Electrodialysis with bipolar membranes is environmentally-friendly separation process that can be suitable way of processing organic acids. When the phenylacetic acid is produced by Gluconobacter oxydans from 2-phenylethanol final fermentation medium consists mostly of phosphate buffer and produced phenylacetic acid. Therefore, electrodialysis with bipolar and anion-exchange membranes can be used for the separation of phenylacetic acid from fermentation broth in one step. Kinetics of phenylacetic acid separation was studied at various temperatures and applied voltages. According to results, phenylacetic acid concentration in diluate was reduced from approximately 4 g/L to approximately 0.34 g/L and in concentrate solution, approximate phenylacetic acid concentration of 3.1 g/L was gained in 240 minutes at 35°C and applied voltage of 30 V.

Název v anglickém jazyce

Separation of phenylacetic acid from fermentation broth by bipolar electrodialysis

Popis výsledku anglicky

The main aim of this work was separation of phenylacetic acid from model solution of fermentation broth by electrodialysis using bipolar membranes. Phenylacetic acid has wide variety of use in pharmaceutical (production of ẞ-lactam, analgesics, etc.), biotechnological and also in perfume industry (honey-like odor). In recent years, a lot of focus was aimed at biotechnological production of organic acids. Thanks to biotechnological production, such product can be labelled as natural according to EU legislation, which affects the product price on the market. However, downstream processing of the final product after bioproduction is often time-consuming and costly. Electrodialysis with bipolar membranes is environmentally-friendly separation process that can be suitable way of processing organic acids. When the phenylacetic acid is produced by Gluconobacter oxydans from 2-phenylethanol final fermentation medium consists mostly of phosphate buffer and produced phenylacetic acid. Therefore, electrodialysis with bipolar and anion-exchange membranes can be used for the separation of phenylacetic acid from fermentation broth in one step. Kinetics of phenylacetic acid separation was studied at various temperatures and applied voltages. According to results, phenylacetic acid concentration in diluate was reduced from approximately 4 g/L to approximately 0.34 g/L and in concentrate solution, approximate phenylacetic acid concentration of 3.1 g/L was gained in 240 minutes at 35°C and applied voltage of 30 V.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

<a href="/cs/project/LO1418" target="_blank" >LO1418: Progresivní rozvoj Membránového inovačního centra</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Workshop of Students´ Presentations 2018

ISBN

978-80-906831-3-6

ISSN

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e-ISSN

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Počet stran výsledku

11

Strana od-do

39-39

Název nakladatele

Czech Membrane Platform

Místo vydání

Česká Lípa

Místo konání akce

Česká Lípa

Datum konání akce

24. 10. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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