Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F28778758%3A_____%2F25%3AN0000001" target="_blank" >RIV/28778758:_____/25:N0000001 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.rsc.org/en/content/articlelanding/2025/ma/d4ma00987h" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2025/ma/d4ma00987h</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d4ma00987h" target="_blank" >10.1039/d4ma00987h</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics

Popis výsledku v původním jazyce

Conductive hydrogels represent a promising class of novel materials to interface the human body with electronics; however, there is still a high demand for hydrogels that would truly meet the conductivity requirements for efficient signal transmission between the tissues and the device. To address this demand, herein we report the preparation of a novel pure conductive hydrogel based on PEDOT:DBSA at room temperature; thus, we offer an efficient alternative to the commonly used PEDOT:PSS, whose biocompatibility was proven to be limited. With thorough characterization, this work also contributes towards a better understanding of the relationship between the hydrogel structure and electrical properties. The mechanical strength of the novel hydrogel network is tuneable and can be easily tailored to the needs of a given application. Together with an exceptionally low value of Young’s modulus, this material provides mechanical properties matching those of soft tissues. Biocompatibility tests confirmed excellent compatibility with murine endothelial cells. The total conductivity of the hydrogel is sufficient for cell-targeted bioelectronic applications, such as cell stimulation; moreover, low impedance was determined at 1 Hz, suggesting that the PEDOT:DBSA hydrogel might offer a truly functional interface between a biological tissue and an electronic device.

Název v anglickém jazyce

Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics

Popis výsledku anglicky

Conductive hydrogels represent a promising class of novel materials to interface the human body with electronics; however, there is still a high demand for hydrogels that would truly meet the conductivity requirements for efficient signal transmission between the tissues and the device. To address this demand, herein we report the preparation of a novel pure conductive hydrogel based on PEDOT:DBSA at room temperature; thus, we offer an efficient alternative to the commonly used PEDOT:PSS, whose biocompatibility was proven to be limited. With thorough characterization, this work also contributes towards a better understanding of the relationship between the hydrogel structure and electrical properties. The mechanical strength of the novel hydrogel network is tuneable and can be easily tailored to the needs of a given application. Together with an exceptionally low value of Young’s modulus, this material provides mechanical properties matching those of soft tissues. Biocompatibility tests confirmed excellent compatibility with murine endothelial cells. The total conductivity of the hydrogel is sufficient for cell-targeted bioelectronic applications, such as cell stimulation; moreover, low impedance was determined at 1 Hz, suggesting that the PEDOT:DBSA hydrogel might offer a truly functional interface between a biological tissue and an electronic device.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Advances

ISSN

—

e-ISSN

2633-5409

Svazek periodika

6

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

1278-1287

Kód UT WoS článku

001401258100001

EID výsledku v databázi Scopus

2-s2.0-85216089644