Surface Nanostructuring of Biopolymers for Tissue Engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F17%3A43893061" target="_blank" >RIV/44555601:13440/17:43893061 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/17:43914236 RIV/44555601:13520/17:43893061

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Surface Nanostructuring of Biopolymers for Tissue Engineering

Popis výsledku v původním jazyce

Surface modification of solid state materials, such as biopolymers, is a process that alters the surface of a material resulting in changes in physical, chemical and biological properties. Many techniques of surface treatment have been developed to improve biopolymer properties, such as wet techniques, plasma exposure or laser treatment. Alternatively, the biopolymer surface can be deposited with metal nanostructures or consequently heated with an application of bioactive substances, such as amino-acids or nanoparticles from solution. The principle of wet methods is a direct contact of a polymer with a reagent to give reactive functional groups or input the metal nanoparticles onto the biopolymer surface. This classic approach for surface treatment usually does not require any special equipment. The aim of grafting is the covalent attachment of suitable groups or macromolecules on the substrate surface. Very often the grafting of thiols is applied, where the thiol group (-SH) improves adhesion of gold nanoparticles on a polymer surface. The major advantage of plasma treatment is its simplicity and affordability. Plasma in contact with the solid material, changes its surface properties (e.g., wetting, metal adhesion, dye ability, chemical inertness, lubricity, and biocompatibility). Functionalization can be performed also as grafting of bioactive molecules, e.g., fullerenes or carbon particles. Effects of excimer laser irradiation on crystallinity and chemical bonding of biodegradable polymer can significantly alter the surface morphology, wettability and biological properties of biopolymers. The several types of structures ranging from simple increase or decrease in surface roughness, wrinkle-like pattern or ripple like pattern can be induced by application of laser treatment. The methods for biopolymer treatment, e.g., treatment of polymers such as poly(lactic acid) (PLA), poly(hydroxybutyrate), poly(glycolic acid), polycaprolactone (PCL) and their blends or copolymers or fibrous polymers such as cellulose or chitosan can significantly alter their cytocompatibility or antimicrobial properties. Improving adhesion characteristics, increasing hydrophobicity, introducing special functional groups at a surface, or modifying the surface morphology are examples of the purposes of these surface treatments. Modified or grafted surfaces may be examined as potential cell carriers for several types of cells.

Název v anglickém jazyce

Surface Nanostructuring of Biopolymers for Tissue Engineering

Popis výsledku anglicky

Surface modification of solid state materials, such as biopolymers, is a process that alters the surface of a material resulting in changes in physical, chemical and biological properties. Many techniques of surface treatment have been developed to improve biopolymer properties, such as wet techniques, plasma exposure or laser treatment. Alternatively, the biopolymer surface can be deposited with metal nanostructures or consequently heated with an application of bioactive substances, such as amino-acids or nanoparticles from solution. The principle of wet methods is a direct contact of a polymer with a reagent to give reactive functional groups or input the metal nanoparticles onto the biopolymer surface. This classic approach for surface treatment usually does not require any special equipment. The aim of grafting is the covalent attachment of suitable groups or macromolecules on the substrate surface. Very often the grafting of thiols is applied, where the thiol group (-SH) improves adhesion of gold nanoparticles on a polymer surface. The major advantage of plasma treatment is its simplicity and affordability. Plasma in contact with the solid material, changes its surface properties (e.g., wetting, metal adhesion, dye ability, chemical inertness, lubricity, and biocompatibility). Functionalization can be performed also as grafting of bioactive molecules, e.g., fullerenes or carbon particles. Effects of excimer laser irradiation on crystallinity and chemical bonding of biodegradable polymer can significantly alter the surface morphology, wettability and biological properties of biopolymers. The several types of structures ranging from simple increase or decrease in surface roughness, wrinkle-like pattern or ripple like pattern can be induced by application of laser treatment. The methods for biopolymer treatment, e.g., treatment of polymers such as poly(lactic acid) (PLA), poly(hydroxybutyrate), poly(glycolic acid), polycaprolactone (PCL) and their blends or copolymers or fibrous polymers such as cellulose or chitosan can significantly alter their cytocompatibility or antimicrobial properties. Improving adhesion characteristics, increasing hydrophobicity, introducing special functional groups at a surface, or modifying the surface morphology are examples of the purposes of these surface treatments. Modified or grafted surfaces may be examined as potential cell carriers for several types of cells.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

20501 - Materials engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Biopolymers: Structure, Performance and Applications

ISBN

978-1-5361-1846-9

Počet stran výsledku

32

Strana od-do

35-66

Počet stran knihy

292

Název nakladatele

Nova Science Publishers, Inc.

Místo vydání

New York

Kód UT WoS kapitoly

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