Up to date production and utilization of plant and animal extracellular vesicles for therapeutic purposes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F25%3A43899197" target="_blank" >RIV/44555601:13440/25:43899197 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/17435889.2025.2511467" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/17435889.2025.2511467</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/17435889.2025.2511467" target="_blank" >10.1080/17435889.2025.2511467</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Up to date production and utilization of plant and animal extracellular vesicles for therapeutic purposes

Popis výsledku v původním jazyce

Extracellular vesicles (EVs) are small, membrane vesicles secreted by cells of variety of organisms and tissues into the extracellular environment. They play a crucial role in intercellular communication. As they move through the extracellular environment, EVs can be taken up by recipient cells within the originating organism or even by cells from other organisms. They can serve as excellent biomarker of physiological or pathological conditions. Over the past few decades, EVs have gained significant attention in biomedical research due to their therapeutic applications. They are able to transport a variety of bioactive molecules ? proteins, lipids, RNAs, synthetic molecules including various drugs, antioxidant or immunomodulatory agent. Their composition, structure, and functional properties vary depending on the source. Currently, methodologies for modifying exosomes, both their content and membrane, are being widely developed so the therapeutic field where EVs can be applied is extremely expanding as well as first clinical trials are ongoing. Other sources of exosomes next to classical as animal or human are being studied, which have impressive therapeutic properties from their origin, e.g., various plant derived extracellular vesicles (PELNVs) [Citation1?4].

Název v anglickém jazyce

Up to date production and utilization of plant and animal extracellular vesicles for therapeutic purposes

Popis výsledku anglicky

Extracellular vesicles (EVs) are small, membrane vesicles secreted by cells of variety of organisms and tissues into the extracellular environment. They play a crucial role in intercellular communication. As they move through the extracellular environment, EVs can be taken up by recipient cells within the originating organism or even by cells from other organisms. They can serve as excellent biomarker of physiological or pathological conditions. Over the past few decades, EVs have gained significant attention in biomedical research due to their therapeutic applications. They are able to transport a variety of bioactive molecules ? proteins, lipids, RNAs, synthetic molecules including various drugs, antioxidant or immunomodulatory agent. Their composition, structure, and functional properties vary depending on the source. Currently, methodologies for modifying exosomes, both their content and membrane, are being widely developed so the therapeutic field where EVs can be applied is extremely expanding as well as first clinical trials are ongoing. Other sources of exosomes next to classical as animal or human are being studied, which have impressive therapeutic properties from their origin, e.g., various plant derived extracellular vesicles (PELNVs) [Citation1?4].

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nanomedicine

ISSN

1743-5889

e-ISSN

1748-6963

Svazek periodika

2025

Číslo periodika v rámci svazku

"necislovano"

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

"nestrankovano"

Kód UT WoS článku

001505286900001

EID výsledku v databázi Scopus

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