Anesthesia type determines risk of cerebral infarction after carotid endarterectomy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F19%3A43895311" target="_blank" >RIV/44555601:13450/19:43895311 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/19:10396137 RIV/61989592:15120/19:73595010 RIV/00179906:_____/19:10396137 RIV/00843989:_____/19:E0107930 RIV/61383082:_____/19:00000485

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0741521418324868?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0741521418324868?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jvs.2018.10.066" target="_blank" >10.1016/j.jvs.2018.10.066</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Anesthesia type determines risk of cerebral infarction after carotid endarterectomy

Popis výsledku v původním jazyce

Objective: Silent and symptomatic cerebral infarctions occur in up to 34% of patients after carotid endarterectomy (CEA). This prospective study compared the risk of new brain infarctions detected by magnetic resonance imaging (MRI) in patients with internal carotid artery stenosis undergoing CEA with local anesthesia (LA) vs general anesthesia (GA). Methods: Consecutive patients with internal carotid artery stenosis indicated for CEA were screened at two centers. Patients without contraindication to LA or GA were randomly allocated to the LA or GA group by ZIP code randomization. Brain MRI was performed before and 24 hours after CEA. Neurologic examination was performed before and 24 hours and 30 days after surgery. The occurrence of new infarctions on the control magnetic resonance images, stroke, transient ischemic attack, and other complications was statistically evaluated. Results: Of 210 randomized patients, 105 underwent CEA with LA (67 men; mean age, 68.3 +- 8.1 years) and 105 with GA (70 men; mean age, 63.4 +- 7.5 years). New infarctions were more frequently detected on control magnetic resonance images in patients after CEA under GA compared with LA (17.1% vs 6.7%; P = .031). Stroke or transient ischemic attack occurred within 30 days of CEA in three patients under GA and in two under LA (P = 1.000). There were no significant differences between the two types of anesthesia in terms of the occurrence of other complications (14.3% for GA and 21.0% for LA; P = .277). Conclusions: The risk of silent brain infarction after CEA as detected by MRI is higher under GA than under LA. (C) 2018 Society for Vascular Surgery

Název v anglickém jazyce

Anesthesia type determines risk of cerebral infarction after carotid endarterectomy

Popis výsledku anglicky

Objective: Silent and symptomatic cerebral infarctions occur in up to 34% of patients after carotid endarterectomy (CEA). This prospective study compared the risk of new brain infarctions detected by magnetic resonance imaging (MRI) in patients with internal carotid artery stenosis undergoing CEA with local anesthesia (LA) vs general anesthesia (GA). Methods: Consecutive patients with internal carotid artery stenosis indicated for CEA were screened at two centers. Patients without contraindication to LA or GA were randomly allocated to the LA or GA group by ZIP code randomization. Brain MRI was performed before and 24 hours after CEA. Neurologic examination was performed before and 24 hours and 30 days after surgery. The occurrence of new infarctions on the control magnetic resonance images, stroke, transient ischemic attack, and other complications was statistically evaluated. Results: Of 210 randomized patients, 105 underwent CEA with LA (67 men; mean age, 68.3 +- 8.1 years) and 105 with GA (70 men; mean age, 63.4 +- 7.5 years). New infarctions were more frequently detected on control magnetic resonance images in patients after CEA under GA compared with LA (17.1% vs 6.7%; P = .031). Stroke or transient ischemic attack occurred within 30 days of CEA in three patients under GA and in two under LA (P = 1.000). There were no significant differences between the two types of anesthesia in terms of the occurrence of other complications (14.3% for GA and 21.0% for LA; P = .277). Conclusions: The risk of silent brain infarction after CEA as detected by MRI is higher under GA than under LA. (C) 2018 Society for Vascular Surgery

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NV16-29148A" target="_blank" >NV16-29148A: Sonolýza v průběhu karotické endarterektomie v prevenci vzniku mozkového infarktu detekovaného pomocí magnetické rezonance - SONOBIRDIE MR Trial</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Vascular Surgery

ISSN

0741-5214

e-ISSN

—

Svazek periodika

70

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

138-147

Kód UT WoS článku

000472167600020

EID výsledku v databázi Scopus

2-s2.0-85061627152