Risk factors for new ischaemic lesions on MR DWI after carotid stenting in patients with efficient antiplatelet therapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F25%3A43899400" target="_blank" >RIV/44555601:13450/25:43899400 - isvavai.cz</a>

Výsledek na webu

<a href="https://cesradiol.cz/artkey/rad-202502-0009_risk-factors-for-new-ischaemic-lesions-on-mr-dwi-after-carotid-stenting-in-patients-with-efficient-antiplatelet.php" target="_blank" >https://cesradiol.cz/artkey/rad-202502-0009_risk-factors-for-new-ischaemic-lesions-on-mr-dwi-after-carotid-stenting-in-patients-with-efficient-antiplatelet.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.55095/CesRadiol2025/017" target="_blank" >10.55095/CesRadiol2025/017</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Risk factors for new ischaemic lesions on MR DWI after carotid stenting in patients with efficient antiplatelet therapy

Popis výsledku v původním jazyce

Aim: To analyse the number, location and clinical significance of new ischaemic lesions after carotid stenting in patients with laboratory-confirmed effective antiplatelet therapy. To evaluate factors leading to thromboembolic complications and silent ischaemia. Methods: We used a retrospective analysis to evaluate a cohort of 171 patients undergoing carotid stenting at the Radiology Department of Masaryk Hospital in Ústí nad Labem between 2014 and 2023. Magnetic resonance imaging with diffusion-weighted images was performed before and after stenting. We evaluated new ischemic lesions after the procedure and their dependence on patient demographics, nature of stenosis, instrumentation used, and antiplatelet therapy. Results: New ischemic lesions were post-procedurally evident in 15.4% of patients (27/171). We recorded five ischemic strokes (2.9%), three of which were of the ?minor stroke? type (1.7%) and two of the ?major stroke? type (1.1%). Most ischemic lesions were located in the ipsilateral middle cerebral artery basin (87.9%), but they also occurred contralaterally or in another basin. Stenosis length ? 15 mm (p = 0.012) and higher degree of stenosis (p = 0.046) were shown to be statistically significantly associated with the development of new ischemic lesions. There was no dependence of the incidence of new ischemic lesions on age (p = 0.511) and stent type (p = 0.574). Conclusion: In a cohort of patients with laboratory-proven effective antiplatelet therapy, new ischemic lesions after carotid stenting are significantly associated with the length and higher degree of stenosis, and are not dependent on the instrumentation used or the demographic characteristics of the cohort. ? 2025, Galen s.r.o.. All rights reserved.

Název v anglickém jazyce

Risk factors for new ischaemic lesions on MR DWI after carotid stenting in patients with efficient antiplatelet therapy

Popis výsledku anglicky

Aim: To analyse the number, location and clinical significance of new ischaemic lesions after carotid stenting in patients with laboratory-confirmed effective antiplatelet therapy. To evaluate factors leading to thromboembolic complications and silent ischaemia. Methods: We used a retrospective analysis to evaluate a cohort of 171 patients undergoing carotid stenting at the Radiology Department of Masaryk Hospital in Ústí nad Labem between 2014 and 2023. Magnetic resonance imaging with diffusion-weighted images was performed before and after stenting. We evaluated new ischemic lesions after the procedure and their dependence on patient demographics, nature of stenosis, instrumentation used, and antiplatelet therapy. Results: New ischemic lesions were post-procedurally evident in 15.4% of patients (27/171). We recorded five ischemic strokes (2.9%), three of which were of the ?minor stroke? type (1.7%) and two of the ?major stroke? type (1.1%). Most ischemic lesions were located in the ipsilateral middle cerebral artery basin (87.9%), but they also occurred contralaterally or in another basin. Stenosis length ? 15 mm (p = 0.012) and higher degree of stenosis (p = 0.046) were shown to be statistically significantly associated with the development of new ischemic lesions. There was no dependence of the incidence of new ischemic lesions on age (p = 0.511) and stent type (p = 0.574). Conclusion: In a cohort of patients with laboratory-proven effective antiplatelet therapy, new ischemic lesions after carotid stenting are significantly associated with the length and higher degree of stenosis, and are not dependent on the instrumentation used or the demographic characteristics of the cohort. ? 2025, Galen s.r.o.. All rights reserved.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká radiologie

ISSN

1210-7883

e-ISSN

—

Svazek periodika

79

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

117-124

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-105008567497