Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F19%3A00008853" target="_blank" >RIV/46747885:24210/19:00008853 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081715:_____/19:00517643 RIV/67985858:_____/19:00517643 RIV/00064165:_____/19:10401966 RIV/00216208:11110/19:10401966 RIV/00023001:_____/19:00078660

Výsledek na webu

<a href="https://pubmed.ncbi.nlm.nih.gov/30918138/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/30918138/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2486/indhealth.2018-0146" target="_blank" >10.2486/indhealth.2018-0146</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides

Popis výsledku v původním jazyce

The aim of this study was to ascertain whether long-term occupational exposure to nanoparticles would affect relative leukocyte telomere length (LrTL). We analysed occupational exposure to size-resolved aerosol particles, with special emphasis on nanoparticles at two workshops: i/ the production of nanocomposites containing metal oxides; ii/ laboratory to test experimental exposure of nano-CuO to rodents. Thirty five exposed researchers (age 39.5 ± 12.6 yr; exposure duration 6.0 ± 3.7 yr) and 43 controls (40.4 ± 10.5 yr) were examined. LrTL did not significantly (p=0.14) differ between the exposed researchers (0.92 ± 0.13) and controls (0.86 ± 0.15). In addition, no significant correlation (r=−0.22, p=0.22) was detected between the duration of occupational exposure and LrTL. The results remained non-significant after multiple adjustments for age, sex and smoking status. Our pilot results suggest that relative leukocyte telomere length is not affected by occupational exposure to nanoparticles.

Název v anglickém jazyce

Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides

Popis výsledku anglicky

The aim of this study was to ascertain whether long-term occupational exposure to nanoparticles would affect relative leukocyte telomere length (LrTL). We analysed occupational exposure to size-resolved aerosol particles, with special emphasis on nanoparticles at two workshops: i/ the production of nanocomposites containing metal oxides; ii/ laboratory to test experimental exposure of nano-CuO to rodents. Thirty five exposed researchers (age 39.5 ± 12.6 yr; exposure duration 6.0 ± 3.7 yr) and 43 controls (40.4 ± 10.5 yr) were examined. LrTL did not significantly (p=0.14) differ between the exposed researchers (0.92 ± 0.13) and controls (0.86 ± 0.15). In addition, no significant correlation (r=−0.22, p=0.22) was detected between the duration of occupational exposure and LrTL. The results remained non-significant after multiple adjustments for age, sex and smoking status. Our pilot results suggest that relative leukocyte telomere length is not affected by occupational exposure to nanoparticles.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30305 - Occupational health

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Industrial Health

ISSN

0019-8366

e-ISSN

—

Svazek periodika

57

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

JP - Japonsko

Počet stran výsledku

3

Strana od-do

741-744

Kód UT WoS článku

000502030800010

EID výsledku v databázi Scopus

2-s2.0-85075749071