Cost-efficient and rapid fabrication of PCB-based microfluidic molds using a CNC approach without cleanroom requirements

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F25%3A00013778" target="_blank" >RIV/46747885:24210/25:00013778 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24620/25:00013778

Výsledek na webu

<a href="https://doi.org/10.1016/j.microc.2025.115015" target="_blank" >https://doi.org/10.1016/j.microc.2025.115015</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.microc.2025.115015" target="_blank" >10.1016/j.microc.2025.115015</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cost-efficient and rapid fabrication of PCB-based microfluidic molds using a CNC approach without cleanroom requirements

Popis výsledku v původním jazyce

A widely utilized approach for manufacturing biomedical microfluidic devices involves the application of soft-lithography technology. Nevertheless, the development of molds for fabricating microfluidic devices, such as SU-8 molds, usually involves a cleanroom environment, which can be rather expensive. Consequently, numerous initiatives have been undertaken to develop inexpensive substitutes for microstructure production, thereby eliminating the need for cleanroom facilities. Non-lithographic low-cost approaches have gained interest from the industrial and research communities for their potential to produce microfluidic structures on a wide scale. These techniques are simple, quick, and cost-effective. In this study, we proposed an efficient method for the mass production of microfluidic devices for determining liquid concentration. Computer numerical control (CNC) micro-milling was the main process and a cost-effective alternative for fabricating microfluidic devices. The study also presents a strategy to remove the burr of the master mold to achieve better quality compared to the standard cleaning and burr removal process. To examine the proposed CNC master mold, printed circuit board (PCB)-based microfluidic devices were fabricated and evaluated. The capability of the device was tested by measuring the capacitance of the liquid concentration. Our findings signify progress towards a cost-effective aluminum master mold with microstructure, intended for the mass production of microfluidic devices. The device potentially valuable basic component for monitoring fluid mixing in microfluidic systems.

Název v anglickém jazyce

Cost-efficient and rapid fabrication of PCB-based microfluidic molds using a CNC approach without cleanroom requirements

Popis výsledku anglicky

A widely utilized approach for manufacturing biomedical microfluidic devices involves the application of soft-lithography technology. Nevertheless, the development of molds for fabricating microfluidic devices, such as SU-8 molds, usually involves a cleanroom environment, which can be rather expensive. Consequently, numerous initiatives have been undertaken to develop inexpensive substitutes for microstructure production, thereby eliminating the need for cleanroom facilities. Non-lithographic low-cost approaches have gained interest from the industrial and research communities for their potential to produce microfluidic structures on a wide scale. These techniques are simple, quick, and cost-effective. In this study, we proposed an efficient method for the mass production of microfluidic devices for determining liquid concentration. Computer numerical control (CNC) micro-milling was the main process and a cost-effective alternative for fabricating microfluidic devices. The study also presents a strategy to remove the burr of the master mold to achieve better quality compared to the standard cleaning and burr removal process. To examine the proposed CNC master mold, printed circuit board (PCB)-based microfluidic devices were fabricated and evaluated. The capability of the device was tested by measuring the capacitance of the liquid concentration. Our findings signify progress towards a cost-effective aluminum master mold with microstructure, intended for the mass production of microfluidic devices. The device potentially valuable basic component for monitoring fluid mixing in microfluidic systems.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/EF16_025%2F0007293" target="_blank" >EF16_025/0007293: Modulární platforma pro autonomní podvozky specializovaných elektrovozidel pro dopravu nákladu a zařízení</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microchemical Journal>

ISSN

0026-265X

e-ISSN

—

Svazek periodika

217

Číslo periodika v rámci svazku

OCT

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

—

Kód UT WoS článku

001595312600015

EID výsledku v databázi Scopus

2-s2.0-105014411153