Polymer Nanofibrous Material for Enzyme Immobilization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F18%3A00005695" target="_blank" >RIV/46747885:24220/18:00005695 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24620/18:00005695

Výsledek na webu

<a href="https://www.scientific.net/MSF.937.129" target="_blank" >https://www.scientific.net/MSF.937.129</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4028/www.scientific.net/MSF.937.129" target="_blank" >10.4028/www.scientific.net/MSF.937.129</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Polymer Nanofibrous Material for Enzyme Immobilization

Popis výsledku v původním jazyce

Nanospider™ method allows preparation of nanofiber sheets with desired specific mass and fiber diameter between 100-600 nm. The fiber diameter can be modified by solvent system, concentration of polymer solution, and external conditions of the electrospinning process, in particular by air humidity and temperature. We have long experience with continual electrospinning from free surface of the polymer solution and in this case we focus on polymer blend polyamide 6/chitosan nanofiber form. Chitosan is an excellent material providing biocompatibility and numerous primary amine groups. On the other hand, polyamide 6 is well known and easy-to-prepare stable polymer guaranteeing sufficient mechanical properties. Blend nanofibers containing synthetic and natural polymers are usually difficult to continuously prepare. Natural polymer bring certain inhomogeneity due to varying chemical and physical properties of each brew. We compared chitosan from four different suppliers and finally fabricated homogenous and long-term stable layers. Successfully prepared nanofiber sheets were used as a support for enzyme immobilization. We showed that our layers can be used as a carrier for numerous biomolecules.

Název v anglickém jazyce

Polymer Nanofibrous Material for Enzyme Immobilization

Popis výsledku anglicky

Nanospider™ method allows preparation of nanofiber sheets with desired specific mass and fiber diameter between 100-600 nm. The fiber diameter can be modified by solvent system, concentration of polymer solution, and external conditions of the electrospinning process, in particular by air humidity and temperature. We have long experience with continual electrospinning from free surface of the polymer solution and in this case we focus on polymer blend polyamide 6/chitosan nanofiber form. Chitosan is an excellent material providing biocompatibility and numerous primary amine groups. On the other hand, polyamide 6 is well known and easy-to-prepare stable polymer guaranteeing sufficient mechanical properties. Blend nanofibers containing synthetic and natural polymers are usually difficult to continuously prepare. Natural polymer bring certain inhomogeneity due to varying chemical and physical properties of each brew. We compared chitosan from four different suppliers and finally fabricated homogenous and long-term stable layers. Successfully prepared nanofiber sheets were used as a support for enzyme immobilization. We showed that our layers can be used as a carrier for numerous biomolecules.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Materials Science Forum

ISBN

978-303571377-0

ISSN

02555476

e-ISSN

—

Počet stran výsledku

7

Strana od-do

129-135

Název nakladatele

Trans Tech Publications Ltd

Místo vydání

—

Místo konání akce

Colombo; Sri Lanka

Datum konání akce

1. 1. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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