Solution-based synthesis of a four-arm star-shaped poly(L-lactide)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F16%3A00003597" target="_blank" >RIV/46747885:24410/16:00003597 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.tandfonline.com/doi/full/10.1080/15685551.2015.1136532" target="_blank" >http://www.tandfonline.com/doi/full/10.1080/15685551.2015.1136532</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/15685551.2015.1136532" target="_blank" >10.1080/15685551.2015.1136532</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Solution-based synthesis of a four-arm star-shaped poly(L-lactide)

Popis výsledku v původním jazyce

The mechanical properties of biocompatible poly(L-lactide) (PLA) could be dramatically enhanced by cross-linking and interesting network structures might be achieved via the formation of branched and star-shaped structures prior to such cross-linking. However, the synthesis of a four-armed star-shaped PLA is limited to bulk melt polymerization at relatively high temperatures that may degrade the monomer and render the reaction kinetics difficult to control. In this work, a solution-based polymerization approach is introduced with dimethylformamide as the solvent for the initiator and all other reactants. Varying the reactant concentrations and reaction temperature, four-arm PLA star structures were produced in solution and their properties were analyzed. The progress of the polymerization reaction was studied using the 1H NMR and Fourier transform infrared spectroscopy. The quantitative evaluation of the monomer conversion was discussed on theoretical basis. The thermal properties and the crystallinity of the product polymers were evaluated using differential scanning calorimetry. Results indicate polymerization and cross-linking of the four-armed PLA were successful. The introduced solution-based method could open venues for better controlled and more economic reactions of star-shaped and cross-linked PLA.

Název v anglickém jazyce

Solution-based synthesis of a four-arm star-shaped poly(L-lactide)

Popis výsledku anglicky

The mechanical properties of biocompatible poly(L-lactide) (PLA) could be dramatically enhanced by cross-linking and interesting network structures might be achieved via the formation of branched and star-shaped structures prior to such cross-linking. However, the synthesis of a four-armed star-shaped PLA is limited to bulk melt polymerization at relatively high temperatures that may degrade the monomer and render the reaction kinetics difficult to control. In this work, a solution-based polymerization approach is introduced with dimethylformamide as the solvent for the initiator and all other reactants. Varying the reactant concentrations and reaction temperature, four-arm PLA star structures were produced in solution and their properties were analyzed. The progress of the polymerization reaction was studied using the 1H NMR and Fourier transform infrared spectroscopy. The quantitative evaluation of the monomer conversion was discussed on theoretical basis. The thermal properties and the crystallinity of the product polymers were evaluated using differential scanning calorimetry. Results indicate polymerization and cross-linking of the four-armed PLA were successful. The introduced solution-based method could open venues for better controlled and more economic reactions of star-shaped and cross-linked PLA.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JJ - Ostatní materiály

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Designed Monomers and Polymers

ISSN

1385-772X

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

180-192

Kód UT WoS článku

000375437000010

EID výsledku v databázi Scopus

2-s2.0-84961286219