How does the surface treatment change the cytocompatibility of implants made by selective laser melting?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F18%3A00001113" target="_blank" >RIV/46747885:24410/18:00001113 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24620/18:00001113

Výsledek na webu

<a href="https://www.tandfonline.com/doi/abs/10.1080/17434440.2018.1456335?journalCode=ierd20" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/17434440.2018.1456335?journalCode=ierd20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/17434440.2018.1456335" target="_blank" >10.1080/17434440.2018.1456335</a>

Jazyk výsledku

angličtina

Název v původním jazyce

How does the surface treatment change the cytocompatibility of implants made by selective laser melting?

Popis výsledku v původním jazyce

Laser Melting technology (SLM). The material tested consisted of the biocompatible titanium alloy Ti6Al4V. The research involved the testing of laboratory specimens produced using SLM technology both in vitro and for surface roughness. The aim of the research was to clarify whether SLM technology affects the cytocompatibility of implants and, thus, whether SLM implants provide suitable candidates for medical use following zero or minimum post-fabrication treatment. Areas covered: The specimens were tested with an osteoblast cell line and, subsequently, two posttreatment processes were compared: non-treated (as-fabricated) and glass-blasted. Interactions with MG-63 cells were evaluated by means of metabolic MTT assay and microscope techniques (scanning electron microscopy, fluorescence microscopy). Surface roughness was observed on both the nontreated and glass-blasted SLM specimens. Expert Commentary: The research concluded that the glass-blasting of SLM Ti6Al4V significantly reduces surface roughness. The arithmetic mean roughness Ra was calculated at 3.4 μm for the glass-blasted and 13.3 μm for the non-treated surfaces. However, the results of in vitro testing revealed that the non-treated surface was better suited to cell growth.

Název v anglickém jazyce

How does the surface treatment change the cytocompatibility of implants made by selective laser melting?

Popis výsledku anglicky

Laser Melting technology (SLM). The material tested consisted of the biocompatible titanium alloy Ti6Al4V. The research involved the testing of laboratory specimens produced using SLM technology both in vitro and for surface roughness. The aim of the research was to clarify whether SLM technology affects the cytocompatibility of implants and, thus, whether SLM implants provide suitable candidates for medical use following zero or minimum post-fabrication treatment. Areas covered: The specimens were tested with an osteoblast cell line and, subsequently, two posttreatment processes were compared: non-treated (as-fabricated) and glass-blasted. Interactions with MG-63 cells were evaluated by means of metabolic MTT assay and microscope techniques (scanning electron microscopy, fluorescence microscopy). Surface roughness was observed on both the nontreated and glass-blasted SLM specimens. Expert Commentary: The research concluded that the glass-blasting of SLM Ti6Al4V significantly reduces surface roughness. The arithmetic mean roughness Ra was calculated at 3.4 μm for the glass-blasted and 13.3 μm for the non-treated surfaces. However, the results of in vitro testing revealed that the non-treated surface was better suited to cell growth.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20506 - Coating and films

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Expert Review of Medical Devices

ISSN

1743-4440

e-ISSN

—

Svazek periodika

15

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

313-321

Kód UT WoS článku

000429225600007

EID výsledku v databázi Scopus

2-s2.0-85044778986