leInfluence of Electrospinning Parameters on the Hydrophilicity of Electrospun Polycaprolactone Nanofibres

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F19%3A00006635" target="_blank" >RIV/46747885:24410/19:00006635 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24620/19:00006635

Výsledek na webu

<a href="https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000011/art00048" target="_blank" >https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000011/art00048</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1166/jnn.2019.16605" target="_blank" >10.1166/jnn.2019.16605</a>

Jazyk výsledku

angličtina

Název v původním jazyce

leInfluence of Electrospinning Parameters on the Hydrophilicity of Electrospun Polycaprolactone Nanofibres

Popis výsledku v původním jazyce

In the present study, PCL (polycaprolactone) nanofibres were produced by the electrospinning method. The use of PCL electrospun biopolymer in biomedical applications has attracted considerable interest due to its chemical resistance, biodegradability, biocompatibility, and non-toxic characteristics. However, the hydrophobic nature of PCL polymer restricts the useage of PCL nanofibres for the cell adhesion and absorption. A hydrophilic and biocompatible PCL electrospun mat with a low water contact angle is an attractive strategy for development in tissue engineering and wound dressing. In this study, we demonstrate a feasible and simple method to produce hydrophilic PCL nanofibres for possible application in wound dressing. Chloroform/ethanol (EtOH) and chloroform/dimethylformamide (DMF) mixtures were used as two different solvent systems. The impact of the polymeric solution concentration, applied voltage, and solvent mixtures on the fibre surface morphology and water contact angle was investigated. Consequently, bead structures were observed at low concentrations but disappeared with increases in the concentration. It was observed that the size of beads decreased and the diameter of fibres increased with increasing voltage. The wettability of the webs changed from hydrophobic to hydrophilic with changes of the polymer concentration. The contact angle of the nanofibre mats decreased in both solvent systems as the concentration increased. The results showed that the lowest contact angle was obtained in 24% wt. PCL chloroform/EtOH solution and was 68°. The highest contact angle was obtained in 4% wt. PCL chloroform/EtOH solution and was 112°. Using this method, the surface hydrophilicity of the PCL nanofibres improved easily without any surface treatment.

Název v anglickém jazyce

leInfluence of Electrospinning Parameters on the Hydrophilicity of Electrospun Polycaprolactone Nanofibres

Popis výsledku anglicky

In the present study, PCL (polycaprolactone) nanofibres were produced by the electrospinning method. The use of PCL electrospun biopolymer in biomedical applications has attracted considerable interest due to its chemical resistance, biodegradability, biocompatibility, and non-toxic characteristics. However, the hydrophobic nature of PCL polymer restricts the useage of PCL nanofibres for the cell adhesion and absorption. A hydrophilic and biocompatible PCL electrospun mat with a low water contact angle is an attractive strategy for development in tissue engineering and wound dressing. In this study, we demonstrate a feasible and simple method to produce hydrophilic PCL nanofibres for possible application in wound dressing. Chloroform/ethanol (EtOH) and chloroform/dimethylformamide (DMF) mixtures were used as two different solvent systems. The impact of the polymeric solution concentration, applied voltage, and solvent mixtures on the fibre surface morphology and water contact angle was investigated. Consequently, bead structures were observed at low concentrations but disappeared with increases in the concentration. It was observed that the size of beads decreased and the diameter of fibres increased with increasing voltage. The wettability of the webs changed from hydrophobic to hydrophilic with changes of the polymer concentration. The contact angle of the nanofibre mats decreased in both solvent systems as the concentration increased. The results showed that the lowest contact angle was obtained in 24% wt. PCL chloroform/EtOH solution and was 68°. The highest contact angle was obtained in 4% wt. PCL chloroform/EtOH solution and was 112°. Using this method, the surface hydrophilicity of the PCL nanofibres improved easily without any surface treatment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/EF16_019%2F0000843" target="_blank" >EF16_019/0000843: Hybridní materiály pro hierarchické struktury</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Nanoscience and Nanotechnology

ISSN

1533-4880

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

7251-7260

Kód UT WoS článku

000475752300047

EID výsledku v databázi Scopus

—