Hyperthermia properties of magnetic polyethylenimine core/shell nanoparticles: influence of carrier and magnetic field strength

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F15%3A00000667" target="_blank" >RIV/46747885:24620/15:00000667 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/article/10.1007/s10965-015-0882-4" target="_blank" >http://link.springer.com/article/10.1007/s10965-015-0882-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10965-015-0882-4" target="_blank" >10.1007/s10965-015-0882-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hyperthermia properties of magnetic polyethylenimine core/shell nanoparticles: influence of carrier and magnetic field strength

Popis výsledku v původním jazyce

Core/shell nanoparticles of magnetic polyethylenimine (MPEI) were prepared by one-step co-precipitation process. MPEI were precipitated by mixing Fe2 /Fe3 solution with polyethylenimine under basic media. The morphology, hydrodynamic size and the phase of the prepared magnetic nanoparticles were characterized using SEM, DLS and XRD, respectively. In addition, the functionality, thermal stability and magnetic properties were assessed using FTIR, TGA and VSM, respectively. The prepared magnetic nanoparticles able to generate local heat under alternative magnetic field caused by the delay in magnetic relaxation provide a benefit in cancer treatment. The strength effects of the applied magnetic field and the different viscosity carriers, namely water and ethanol, on the heating ability were investigated. It was an obvious rise of temperature by increasing in strength of applied magnetic field and by the exposure time. Heat transfer to the fluid was hindered by the viscosity of the carrier. The viscosity affects the heating properties through a Brownian mechanism and thus causes a significant specific absorption rate (SAR). The heating properties of the prepared MPEI nanoparticles with the highest SAR value (177.48 Wg−1) show their potential in hyperthermia application.

Název v anglickém jazyce

Hyperthermia properties of magnetic polyethylenimine core/shell nanoparticles: influence of carrier and magnetic field strength

Popis výsledku anglicky

Core/shell nanoparticles of magnetic polyethylenimine (MPEI) were prepared by one-step co-precipitation process. MPEI were precipitated by mixing Fe2 /Fe3 solution with polyethylenimine under basic media. The morphology, hydrodynamic size and the phase of the prepared magnetic nanoparticles were characterized using SEM, DLS and XRD, respectively. In addition, the functionality, thermal stability and magnetic properties were assessed using FTIR, TGA and VSM, respectively. The prepared magnetic nanoparticles able to generate local heat under alternative magnetic field caused by the delay in magnetic relaxation provide a benefit in cancer treatment. The strength effects of the applied magnetic field and the different viscosity carriers, namely water and ethanol, on the heating ability were investigated. It was an obvious rise of temperature by increasing in strength of applied magnetic field and by the exposure time. Heat transfer to the fluid was hindered by the viscosity of the carrier. The viscosity affects the heating properties through a Brownian mechanism and thus causes a significant specific absorption rate (SAR). The heating properties of the prepared MPEI nanoparticles with the highest SAR value (177.48 Wg−1) show their potential in hyperthermia application.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JI - Kompositní materiály

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Polymer Research

ISSN

1572-8935

e-ISSN

—

Svazek periodika

22

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

""

Kód UT WoS článku

000365422500002

EID výsledku v databázi Scopus

2-s2.0-84947580706