Carbon nanostructures grafted biopolymers for medical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F19%3A00006805" target="_blank" >RIV/46747885:24620/19:00006805 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/44555601:13440/19:43894733 RIV/60461373:22310/19:43919003

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/10667857.2019.1573943" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/10667857.2019.1573943</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10667857.2019.1573943" target="_blank" >10.1080/10667857.2019.1573943</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Carbon nanostructures grafted biopolymers for medical applications

Popis výsledku v původním jazyce

Enhancing biopolymers with carbon nanostructures leads to the creation of attractive materials suitable for diverse medical application. We studied surface properties and cytocompatibility of amine functionalised carbon nanoparticles (CNPs) grafted on biopolymer film. Poly-L-lactic acid and poly-3-hydroxybutyrate were treated in an inert argon plasma discharge and subsequently grafted with three types of amine-functionalised CNPs. The surface properties of (i) CNPs and (ii) grafted CNPs were studied using multiple methods. BET, electrokinetic and XPS analyses confirmed the successful grafting of amino-compounds on the surface and also into the pores of CNPs. Goniometry approved the binding of themodified CNPs on the polymer surface. FromAFM is evident that both the biopolymers show completely changed surface morphology after grafting of CNPs. The cytocompatibility test with vascular smooth muscle cells showed that the presence of the modified CNPs on polymer substrates has a more positive effect on cytocompatibility of PLLA rather than PHB.

Název v anglickém jazyce

Carbon nanostructures grafted biopolymers for medical applications

Popis výsledku anglicky

Enhancing biopolymers with carbon nanostructures leads to the creation of attractive materials suitable for diverse medical application. We studied surface properties and cytocompatibility of amine functionalised carbon nanoparticles (CNPs) grafted on biopolymer film. Poly-L-lactic acid and poly-3-hydroxybutyrate were treated in an inert argon plasma discharge and subsequently grafted with three types of amine-functionalised CNPs. The surface properties of (i) CNPs and (ii) grafted CNPs were studied using multiple methods. BET, electrokinetic and XPS analyses confirmed the successful grafting of amino-compounds on the surface and also into the pores of CNPs. Goniometry approved the binding of themodified CNPs on the polymer surface. FromAFM is evident that both the biopolymers show completely changed surface morphology after grafting of CNPs. The cytocompatibility test with vascular smooth muscle cells showed that the presence of the modified CNPs on polymer substrates has a more positive effect on cytocompatibility of PLLA rather than PHB.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Technology

ISSN

1066-7857

e-ISSN

—

Svazek periodika

34

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

376-385

Kód UT WoS článku

000467883400002

EID výsledku v databázi Scopus

2-s2.0-85065405746