The Black-White Pixels Ratio in Medial Temporal Lobe Brain Structure in Transcranial B-Images as a Measurable Marker of Alzheimer's Disease Probability: The Reproducibility Overview

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F47813059%3A19240%2F20%3AA0000675" target="_blank" >RIV/47813059:19240/20:A0000675 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/26867184:_____/20:N0000023

Výsledek na webu

<a href="https://ieeexplore.ieee.org/document/9238214" target="_blank" >https://ieeexplore.ieee.org/document/9238214</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23919/SoftCOM50211.2020.9238214" target="_blank" >10.23919/SoftCOM50211.2020.9238214</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Black-White Pixels Ratio in Medial Temporal Lobe Brain Structure in Transcranial B-Images as a Measurable Marker of Alzheimer's Disease Probability: The Reproducibility Overview

Popis výsledku v původním jazyce

The objective of the presented study is to introduce analysis the black-white pixels ratio in medial temporal lobe (MTL) brain structure in digitized transcranial B-images using our developed software B-MODE Assist. This ratio could be a significant marker related to the echogenicity grade. In B-image, the MTL is stable anechogenic structure but increased echogenicity of surrounding cortex is detectable in the case of MTL atrophy; the atrophy predicts Alzheimer's Disease. Within this study, a set of 97 B-images is used. There are two key goals of this pilot study; verify the reproducibility of the ratio between two observers and to show that the ratio is not much different in the case of original image in comparison with a magnified segment and using constant brightness increasing; the ratio should be independent on image resolution and brightness. To select medial temporal lobe structure, a 20mm square-shaped Region of Interest is used. The correlation coefficient r=0.69 was achieved between two independent, non-experienced observers. The error does not exceed 28 % between 2 non-experienced observers and does not exceed 12 % between the measurements from the same observer. Also, the variance and the range were computed. Achieved results have been judged by an experienced sonographer. In the future, the ratio could be an effective value to determine the MTL atrophy based on the ratio value and possibility to create a rule-based expert system which should help evaluate probability of Alzheimer's Disease based on the cortex echogenicity grade. In general, this approach could be a reliable way to detect risk of Alzheimer's Disease using neurosonological imaging.

Název v anglickém jazyce

The Black-White Pixels Ratio in Medial Temporal Lobe Brain Structure in Transcranial B-Images as a Measurable Marker of Alzheimer's Disease Probability: The Reproducibility Overview

Popis výsledku anglicky

The objective of the presented study is to introduce analysis the black-white pixels ratio in medial temporal lobe (MTL) brain structure in digitized transcranial B-images using our developed software B-MODE Assist. This ratio could be a significant marker related to the echogenicity grade. In B-image, the MTL is stable anechogenic structure but increased echogenicity of surrounding cortex is detectable in the case of MTL atrophy; the atrophy predicts Alzheimer's Disease. Within this study, a set of 97 B-images is used. There are two key goals of this pilot study; verify the reproducibility of the ratio between two observers and to show that the ratio is not much different in the case of original image in comparison with a magnified segment and using constant brightness increasing; the ratio should be independent on image resolution and brightness. To select medial temporal lobe structure, a 20mm square-shaped Region of Interest is used. The correlation coefficient r=0.69 was achieved between two independent, non-experienced observers. The error does not exceed 28 % between 2 non-experienced observers and does not exceed 12 % between the measurements from the same observer. Also, the variance and the range were computed. Achieved results have been judged by an experienced sonographer. In the future, the ratio could be an effective value to determine the MTL atrophy based on the ratio value and possibility to create a rule-based expert system which should help evaluate probability of Alzheimer's Disease based on the cortex echogenicity grade. In general, this approach could be a reliable way to detect risk of Alzheimer's Disease using neurosonological imaging.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20206 - Computer hardware and architecture

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

2020 International Conference on Software, Telecommunications and Computer Networks (SoftCOM)

ISBN

9781728175386

ISSN

—

e-ISSN

1847-358X

Počet stran výsledku

6

Strana od-do

1-6

Název nakladatele

Institute of Electrical and Electronics Engineers Inc.

Místo vydání

Croatia

Místo konání akce

Split, Hvar; Croatia

Datum konání akce

1. 1. 2020

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

—