Constitutive modelling of an arterial wall supported by microscopic measurements

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F11%3A43899225" target="_blank" >RIV/49777513:23520/11:43899225 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Constitutive modelling of an arterial wall supported by microscopic measurements

Popis výsledku v původním jazyce

An idealized model of an arterial wall is proposed as a two-layer system. Distinct mechanical response of each layer is taken into account considering two types of strain energy functions in the hyperelasticity framework. The outer layer, considered as fiber-reinforced composite, is modelled using the structural model of Holzapfel et al. The inner layer, on the other hand, is represented by a two-scale model mimicing smooth muscle tissue. For the latter one, several material parameters such as shape, volume fraction and orientation of smooth muscle cells are determined using the microscopic measurements. Good agreement of predicted mechanical response with experimental data is promising for further progress.

Název v anglickém jazyce

Constitutive modelling of an arterial wall supported by microscopic measurements

Popis výsledku anglicky

An idealized model of an arterial wall is proposed as a two-layer system. Distinct mechanical response of each layer is taken into account considering two types of strain energy functions in the hyperelasticity framework. The outer layer, considered as fiber-reinforced composite, is modelled using the structural model of Holzapfel et al. The inner layer, on the other hand, is represented by a two-scale model mimicing smooth muscle tissue. For the latter one, several material parameters such as shape, volume fraction and orientation of smooth muscle cells are determined using the microscopic measurements. Good agreement of predicted mechanical response with experimental data is promising for further progress.

Druh

O - Ostatní výsledky

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/GA106%2F09%2F0734" target="_blank" >GA106/09/0734: Vliv mikroskopického uspořádání tkání a funkce buněčného cytoskeletu na mechanické vlastnosti živých tkání</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů