Modelling of blood's non-newtonian behaviour in patient-specific aorto-coronary bypass grafts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43915349" target="_blank" >RIV/49777513:23520/12:43915349 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Modelling of blood's non-newtonian behaviour in patient-specific aorto-coronary bypass grafts

Popis výsledku v původním jazyce

The patency and overall performance of implanted bypass grafts is closely related to hemodynamics and its influence on vessel remodelling. In this regard, numerical investigation of blood flow in models reconstructed from clinical data may, next to clinical research, provide a valuable insight into the problem of graft failures, which are usually associated with restenosis and/or occlusive intimal hyperplasia. In this study, numerical results of pulsatile non-Newtonian blood flow in three realistic aorto-coronary bypass models are presented and further discussed with emphasis placed on the distribution of wall shear stress (WSS) and oscillatory shear index (OSI). Blood's shear-thinning behaviour is described by the Carreau-Yasuda model. Assuming all model walls to be impermeable and inelastic, the numerical solution of the mathematical model, which has the form of time-dependent non-linear systém of Navier-Stokes (NS) equations, is carried out on the basis of the three-stage fractional

Název v anglickém jazyce

Modelling of blood's non-newtonian behaviour in patient-specific aorto-coronary bypass grafts

Popis výsledku anglicky

The patency and overall performance of implanted bypass grafts is closely related to hemodynamics and its influence on vessel remodelling. In this regard, numerical investigation of blood flow in models reconstructed from clinical data may, next to clinical research, provide a valuable insight into the problem of graft failures, which are usually associated with restenosis and/or occlusive intimal hyperplasia. In this study, numerical results of pulsatile non-Newtonian blood flow in three realistic aorto-coronary bypass models are presented and further discussed with emphasis placed on the distribution of wall shear stress (WSS) and oscillatory shear index (OSI). Blood's shear-thinning behaviour is described by the Carreau-Yasuda model. Assuming all model walls to be impermeable and inelastic, the numerical solution of the mathematical model, which has the form of time-dependent non-linear systém of Navier-Stokes (NS) equations, is carried out on the basis of the three-stage fractional

Druh

O - Ostatní výsledky

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0090" target="_blank" >ED1.1.00/02.0090: NTIS - Nové technologie pro informační společnost</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů