Modelling of the smooth muscle and Cajal's cells communication in the bladder wall
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43916303" target="_blank" >RIV/49777513:23520/12:43916303 - isvavai.cz</a>
Výsledek na webu
—
DOI - Digital Object Identifier
—
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Modelling of the smooth muscle and Cajal's cells communication in the bladder wall
Popis výsledku v původním jazyce
To model the pathological events in the lower part of urinary tract like the overactive bladder (OAB) and detrusor overactivity (DO) seems to be necessary to take in to account all cellular types present in the detrusor tissue. Besides the smooth musclecells (SMC) there are here the interstitial cells of Cajal. According to the last investigations the ICC are involved in the spontaneous contractile activity during filling. They communicate with the nerves and are connected via gap junctions with the SMC. In contribution the mathematical models of SMC and ICC are introduced and models of their connection are suggested. The properties of the whole model consisting from ICC, SMC are analyzed and compared with the published experimental results.
Název v anglickém jazyce
Modelling of the smooth muscle and Cajal's cells communication in the bladder wall
Popis výsledku anglicky
To model the pathological events in the lower part of urinary tract like the overactive bladder (OAB) and detrusor overactivity (DO) seems to be necessary to take in to account all cellular types present in the detrusor tissue. Besides the smooth musclecells (SMC) there are here the interstitial cells of Cajal. According to the last investigations the ICC are involved in the spontaneous contractile activity during filling. They communicate with the nerves and are connected via gap junctions with the SMC. In contribution the mathematical models of SMC and ICC are introduced and models of their connection are suggested. The properties of the whole model consisting from ICC, SMC are analyzed and compared with the published experimental results.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
BK - Mechanika tekutin
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů