Segmental differences in the orientation of smooth muscle cells in the tunica media of porcine aortae

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F15%3A43924890" target="_blank" >RIV/49777513:23520/15:43924890 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/49777513:23640/15:43924890

Výsledek na webu

<a href="http://link.springer.com/article/10.1007/s10237-014-0605-5" target="_blank" >http://link.springer.com/article/10.1007/s10237-014-0605-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10237-014-0605-5" target="_blank" >10.1007/s10237-014-0605-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Segmental differences in the orientation of smooth muscle cells in the tunica media of porcine aortae

Popis výsledku v původním jazyce

The orientation of vascular smooth muscle cells of porcine aortae was assessed to test the widely accepted assumption that these smooth muscle cells are arranged in two helices. We used tangential histological sections of 82 samples of five anatomical segments of thoracic and abdominal porcine aortae and three age groups in animals ranging in age from 5-210 days. The distribution of the orientation of smooth muscle cell nuclei in five proximodistal segments of the porcine aortae was determined using analgorithm that fitted a mixture of one to five von Mises probability distributions of the data retrieved from histological micrographs. Automated tracking of the nuclei was confirmed by and consistent with manual histological analysis. The orientation ofthe vascular smooth muscle cells was successfully fitted using two von Mises distributions in most of the samples with different ages, wall thicknesses, and anatomical positions, which corresponds to two populations of vascular smooth mu

Název v anglickém jazyce

Segmental differences in the orientation of smooth muscle cells in the tunica media of porcine aortae

Popis výsledku anglicky

The orientation of vascular smooth muscle cells of porcine aortae was assessed to test the widely accepted assumption that these smooth muscle cells are arranged in two helices. We used tangential histological sections of 82 samples of five anatomical segments of thoracic and abdominal porcine aortae and three age groups in animals ranging in age from 5-210 days. The distribution of the orientation of smooth muscle cell nuclei in five proximodistal segments of the porcine aortae was determined using analgorithm that fitted a mixture of one to five von Mises probability distributions of the data retrieved from histological micrographs. Automated tracking of the nuclei was confirmed by and consistent with manual histological analysis. The orientation ofthe vascular smooth muscle cells was successfully fitted using two von Mises distributions in most of the samples with different ages, wall thicknesses, and anatomical positions, which corresponds to two populations of vascular smooth mu

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BB - Aplikovaná statistika, operační výzkum

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomechanics and Modeling in Mechanobiology

ISSN

1617-7959

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

18

Strana od-do

315-332

Kód UT WoS článku

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EID výsledku v databázi Scopus

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