Microscopic image analysis of elastin network in samples of normal, atherosclerotic and aneurysmatic abdominal aorta and its biomechanical implications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F03%3A00000034" target="_blank" >RIV/49777513:23640/03:00000034 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/03:00000055 RIV/00216208:11140/03:00003345

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Microscopic image analysis of elastin network in samples of normal, atherosclerotic and aneurysmatic abdominal aorta and its biomechanical implications

Popis výsledku v původním jazyce

We assessed the proportions of smooth muscle cells, elastin and collagen in histological sections of aorta samples and studied the morphological characteristics of the elastin network in the tunica media. A new method was introduced for the assessment ofstructures formed by elastin membranes and fibres, using the fast Fourier transform (FFT) technique. The results of this comparative study, obtained from selected samples from 24 patients, revealed that the percentage values of the constituents of the arterial wall can not distinguish between the preserved segments of normal, atherosclerotic or aneurysmatic aorta. The results of the Fourier analysis proved that the FFT provided an efficient method for evaluating cross sections of the elastin m embranesand fibres, reflecting their anisotropy. We discuss the methodological difficulties and biomechanical implications of our work as well compare it to other methods of elastin analysis.

Název v anglickém jazyce

Microscopic image analysis of elastin network in samples of normal, atherosclerotic and aneurysmatic abdominal aorta and its biomechanical implications

Popis výsledku anglicky

We assessed the proportions of smooth muscle cells, elastin and collagen in histological sections of aorta samples and studied the morphological characteristics of the elastin network in the tunica media. A new method was introduced for the assessment ofstructures formed by elastin membranes and fibres, using the fast Fourier transform (FFT) technique. The results of this comparative study, obtained from selected samples from 24 patients, revealed that the percentage values of the constituents of the arterial wall can not distinguish between the preserved segments of normal, atherosclerotic or aneurysmatic aorta. The results of the Fourier analysis proved that the FFT provided an efficient method for evaluating cross sections of the elastin m embranesand fibres, reflecting their anisotropy. We discuss the methodological difficulties and biomechanical implications of our work as well compare it to other methods of elastin analysis.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

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Projekt

<a href="/cs/project/LN00B084" target="_blank" >LN00B084: Nové technologie Výzkumné centrum v Západočeském regionu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

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Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

12

Strana od-do

149-160

Kód UT WoS článku

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EID výsledku v databázi Scopus

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