Fluorescent carbon nanoparticles in cancer diagnostic and therapy systems

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F24%3A43975706" target="_blank" >RIV/49777513:23640/24:43975706 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/B9780443135910000176" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/B9780443135910000176</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-443-13591-0.00017-6" target="_blank" >10.1016/B978-0-443-13591-0.00017-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fluorescent carbon nanoparticles in cancer diagnostic and therapy systems

Popis výsledku v původním jazyce

Fluorescent carbon nanoparticles (FCNPs) have emerged as a promising class of nanomaterials for cancer theranostic, combining diagnostic and therapeutic capabilities into a single platform. These nanoparticles (NPs) possess unique optical properties, including tunable fluorescence emission, excellent photostability, and low cytotoxicity, making them attractive for bioimaging and sensing applications. Additionally, FCNPs can act as nanocarriers for delivering chemotherapeutic drugs, gene therapeutics, or photosensitizers for photodynamic therapy. This typical chapter comprehensively overviews the latest developments using FCNPs for cancer diagnosis and treatment. We discuss the various synthesis methods, surface functionalization strategies, and the mechanisms underlying their fluorescence behavior. The applications of FcnPs in cancer cell imaging, tumor targeting, and drug delivery are highlighted, focusing on their ability to enhance the specificity and efficacy of cancer treatment. Recent advances in developing multifunctional FCNPs for multimodal imaging, combined chemo-photodynamic therapy, and stimuli-responsive drug release have also been explored. Furthermore, the challenges and perspectives associated with the clinical translation of FCNPs-based theranostic systems, including biocompatibility, biodistribution, and clearance considerations were addressed. Overall, this chapter underscores the significant potential of FCNPs as versatile nanoplatforms for integrated cancer diagnosis and therapy, paving the way for personalized and targeted cancer management strategies.

Název v anglickém jazyce

Fluorescent carbon nanoparticles in cancer diagnostic and therapy systems

Popis výsledku anglicky

Fluorescent carbon nanoparticles (FCNPs) have emerged as a promising class of nanomaterials for cancer theranostic, combining diagnostic and therapeutic capabilities into a single platform. These nanoparticles (NPs) possess unique optical properties, including tunable fluorescence emission, excellent photostability, and low cytotoxicity, making them attractive for bioimaging and sensing applications. Additionally, FCNPs can act as nanocarriers for delivering chemotherapeutic drugs, gene therapeutics, or photosensitizers for photodynamic therapy. This typical chapter comprehensively overviews the latest developments using FCNPs for cancer diagnosis and treatment. We discuss the various synthesis methods, surface functionalization strategies, and the mechanisms underlying their fluorescence behavior. The applications of FcnPs in cancer cell imaging, tumor targeting, and drug delivery are highlighted, focusing on their ability to enhance the specificity and efficacy of cancer treatment. Recent advances in developing multifunctional FCNPs for multimodal imaging, combined chemo-photodynamic therapy, and stimuli-responsive drug release have also been explored. Furthermore, the challenges and perspectives associated with the clinical translation of FCNPs-based theranostic systems, including biocompatibility, biodistribution, and clearance considerations were addressed. Overall, this chapter underscores the significant potential of FCNPs as versatile nanoplatforms for integrated cancer diagnosis and therapy, paving the way for personalized and targeted cancer management strategies.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Fluorescent Carbon Nanoparticles: Fundamentals and Applications

ISBN

978-0-443-13591-0

Počet stran výsledku

49

Strana od-do

367-415

Počet stran knihy

867

Název nakladatele

Elsevier

Místo vydání

Nizozemí

Kód UT WoS kapitoly

—