Biomedically relevant chemical constituents of Valeriana officinalis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F10%3A00012128" target="_blank" >RIV/60076658:12110/10:00012128 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41320/10:18259

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biomedically relevant chemical constituents of Valeriana officinalis

Popis výsledku v původním jazyce

Valerian is used against sleeping disorders, restlessness and anxiety. Valerian seems only to work when taken over longer periods (several weeks). Some studies have demonstrated that valerian extracts interact with the GABA and benzodiazepine receptors.Valerian is also used traditionally to treat gastrointestinal pain and spastic colitis. Long term safety studies are missing. Valerian contains over 150 chemical constituents and many of them are physiologically active, mainly pyridine alkaloids, some organic acids and terpenes, especially so called valepotriates, esterified iridoid-monoterpenes. As valepotriates may be potential mutagens, valerian should only be used after consultation with a physician. Valerian medication is sometimes recommended as first line when benefit-risk relation requires so. Valerian is often indicated as transition medication during discontinuation processes involving bromazepam, clonazepam and diazepam, among others.

Název v anglickém jazyce

Biomedically relevant chemical constituents of Valeriana officinalis

Popis výsledku anglicky

Valerian is used against sleeping disorders, restlessness and anxiety. Valerian seems only to work when taken over longer periods (several weeks). Some studies have demonstrated that valerian extracts interact with the GABA and benzodiazepine receptors.Valerian is also used traditionally to treat gastrointestinal pain and spastic colitis. Long term safety studies are missing. Valerian contains over 150 chemical constituents and many of them are physiologically active, mainly pyridine alkaloids, some organic acids and terpenes, especially so called valepotriates, esterified iridoid-monoterpenes. As valepotriates may be potential mutagens, valerian should only be used after consultation with a physician. Valerian medication is sometimes recommended as first line when benefit-risk relation requires so. Valerian is often indicated as transition medication during discontinuation processes involving bromazepam, clonazepam and diazepam, among others.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/QH81160" target="_blank" >QH81160: Ekonomická efektivnost šlechtění lesních dřevin</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

000274244600002

EID výsledku v databázi Scopus

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